HD Insights™

H D I N S I G H T S EDITOR'S LETTER Welcome to the fourth edition of HD Insights! We started the venture of this periodical in 2011 and we have received great feedback on the first three issues. We electronically distribute every issue to over 1300 investigators, researchers, clinicians, and industry leaders from around the globe. In addition to electronic distribution, in 2011, 300 hard copies were distributed at the Huntington Study Group meeting in Indianapolis, Indiana, USA. In 2012, 700 hard copies were distributed at the European Huntington Disease Network meeting in Stockholm, Sweden; and also in 2012, 300 hard copies were distributed at the Huntington Study Group Meeting in Seattle, Washington, USA. Past issues of HD Insights are available at www.hdinsights.org. They include interviews with leaders in the field such as Dr. Nancy Wexler, Professor of Neuropsychology at Columbia University, and Dr. Walter Koroshetz, the Deputy Director of the NINDS. There are articles on how many people in the world have HD; the therapeutic promises and challenges of antisense oligonucleotides; profiles of companies developing therapies for HD, such as Prana Biotechnology and Isis Pharmaceuticals; and status updates of HD clinical trials, the only comprehensive status report of HD clinical trials globally. In this issue and the previous issue, we have included features on HD research in Chile and Japan. If you or one of your colleagues are interested in contributing a piece that highlights HD research in your part of the globe, please email me at editor@hdinsights.org. To receive a free subscription to HD Insights, simply email subscribe@hdinsights.org. If you have feedback for HD Insights, if there are features you would like to see in the next issue, if you want to contribute an article, or if you are eager to support this periodical, please email me. The continuation of this periodical into 2013 has again been made possible by a generous unrestricted educational grant from Lundbeck. Together we can advance research and eventually therapeutics for Huntington disease. -- R AY D O R S E Y , M D E D I T O R , H D I N S I G H T S TM Editorial Board Members Contributors Ray Dorsey, MD — Editor, Johns Hopkins University Donald Kennedy, PhD — Stanford University Nobuyuki Nukina, MD, PhD — Riken Brain Science Institute Rodrigo Osorio — Agrupacion Chilena de Huntington Bernard Ravina, MD — Biogen Idec Ralf Reilmann, MD — University of Munster Sarah Tabrizi, MBChB, PhD — University College London Leslie Thompson, PhD — University of California Irvine Hitoshi Okazawa, MD, PhD Justo Garcia de Yebenes, MD Lise Munsie, PhD Paige Nichols, BA Huntington Study Group Shari Kinel, JD — HSG Executive Director Liz McCarthy, BA — HSG Administrative Manager Jillian Lowell, BS — HSG Event Planner Publication Staff Kristin Darwin, BS — Deputy Editor Robin Taylor — Production Editor Martin Holmes — Technical Editor Todd Bernhard — Copy Editor Vinayak Venkataraman, BS — Website Designer Dave Kolko — Distribution Specialist For more information on HD Insights, or to receive a free subscription, please visit us at www.HDInsights.org or email us at editor@hdinsights.org. 12 Copyright © Huntington Study Group 2013. All rights reserved. HD Insights, Vol. 4

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