HD Insights™

Vol. 9 - Winter 2014

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Editorial Board Members Ray Dorsey, MD — Editor, University of Rochester Donald Kennedy, PhD — Stanford University Nobuyuki Nukina, MD, PhD — Riken Brain Science Institute Rodrigo Osorio — Agrupación Chilena de Huntington Bernard Ravina, MD — Voyager Therapeutics Ralf Reilmann, MD, PhD — George Huntington Institute Sarah Tabrizi, MBChB, PhD — University College London Leslie Thompson, PhD — University of California Irvine Huntington Study Group Shari Kinel, JD — HSG Executive Director Liz McCarthy, BA — HSG Administrative Manager For more information on HD Insights, or to receive a free subscription, please visit us at www.hdinsights.org or email us at editor@hdinsights.org. Welcome to the 9th edition of HD Insights. We are grateful to the Huntington Study Group (HSG), our sponsors, and our over 2,500 subscribers for their continuing support of our mission. In this special edition, we feature Dr. Ira Shoulson, founder and leader of the HSG from 1996 to 2014. Dr. Shoulson's leadership and vision have been powerful forces for HD research for forty years. HD Insights also brings you the nominees and winners of the first Insights of the Year competition. The HD Insights staff and expert HD researchers nominated eleven papers published between July 2013 and July 2014 in HD basic science, clinical research, and biomarkers research, for consideration by our Editorial Board. The Board voted on the papers to select the most influential paper in each category. As a result, Drs. Francesca Cicchetti, Chris S. Tang, and X. William Yang will be presenting their winning research in a special panel session at the HSG meeting. In addition to these highlights, we bring you an interview with Ms. Julie Smith, President and CEO (designate) of Raptor Pharmaceuticals, who tells of her hopes for the company's ongoing clinical trial with cysteamine bitartrate in HD. Our interview with Ms. Smith was edited by our newest team member, Associate Editor Ryan Korn, whose contributions we will feature in the coming year. HD Insights relies on the support of firms dedicated to developing novel treatments to bring the latest research to the international HD research community. If you are interested in becoming a supporter, please contact me at editor@hdinsights.org. We welcome new contributors, suggestions for topics, and ideas about how we can better serve you. If you or someone you know would like to share their ideas with over 2,500 HD researchers and clinicians around the world, please contact me at editor@hdinsights.org. Finally, subscription to HD Insights is always free: simply send us an email at subscribe@hdinsights.org. - - R A Y D O R S E Y , M D E D I T O R , H D I N S I G H T S T M H D D I S C L O S U R E S : D R . D O R S E Y R E C E I V E S G R A N T S U P P O R T F R O M P R A N A B I O T E C H N O L O G Y A N D A U S P E X P H A R M A C E U T I C A L S . E D I T O R ' S L E T T E R Copyright © Huntington Study Group 2014. All rights reserved. Contributors Meredith A. Achey, BM Francesca Cicchetti, PhD Laura E. Clemens Christina Colletta, BA Nellie Georgiou-Karistianis, PhD Flaviano Giogini, PhD Victoria Gonzalez, MD, PhD Steven M. Hersch, MD, PhD Erik K. H. Jansson Robert Mason, PhD Miriam Moscovitch-Lopatin, PhD, PMP Lise Munsie, PhD H. Diana Rosas, MD Chris C. Tang, MD, PhD X. William Yang, MD, PhD Publication Staff Meredith A. Achey, BM — Deputy Editor Ryan Korn, BA — Associate Editor Robin Taylor — Production Editor Martin Holmes — Technical Editor David Kolko — Distribution Specialist H D I N S I G H T S HD Insights, Vol. 9 20

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