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Tablets & Capsules Solid Dosage SourceBook June 2015 73 Material Flow Solutions Corporate Description Material Flow Solutions supplies cost effective engineered solutions based on measurement of key material flow properties. We provide property testing combined with nearly 40 years of design experience to solve flow problems facing producers of fine powders and granules in the pharmaceutical, food, chemical, energy, mining, and consumer products industries. Markets Served Chemical, Food and Pharmaceutical Areas of excellence: Bulk solids handling. With decades of experience in the powder and particle industry, we recognized the need for advancement in two very specific areas. • Segregation potential measurement and prediction of REAL mixtures – not simple bimodal mixtures, but mixtures of multiple components. • Powder Flowability measurement at product formulation time – at contact pressures low enough to correlate with REAL tablet/capsule fill systems – and in sample quantities small enough to be affordable when high- cost preliminary production quantities are all that is available. We met the need by developing the SPECTester segregation quantifier and the SSSpinTester strength and density analyzer. Major products or services In-House Testing Laboratory Our extensive list of in-house testing capabilities for powders and granular materials includes: • unconfined yield strength, friction angle, adhesion, bulk density and permeability measurement, • wear testing • moisture sorption analysis • thermal conductivity and heat capacity • segregation and blending analyses • attrition and size degradation Material Flow Solutions 5921 N County Road 225 Gainesville, FL 32609 Tel: 352 303 9123 FAX: 352 379 8878 Email: Website: • circularity and granularity analysis • zeta potential, • particle size and shape analysis, • particle toxicology studies If you have a particle, we can characterize it. SPECTester Using the spectral reflectance value of the unique ingredients, as well as the whole mixtures, the SPECTester quantifies the segregation potential of a 6-component material. In under 30 minutes, the machine reports how much as well as why your material is segregating. Fully automated, it provides data about: component concentrations, particle size differences, product uniformity, and up to 4 specific segregation mechanisms. SSSpinTester Using the science of centrifugal force, the SSSpinTester measures the unconfined yield strength and density of fine powders using a sample as small as 0.05 gram. New technology extends the testing range down to 0.2 KPA compaction pressure, which allows direct measurement for arching potential – eliminating the need to rely on inherently inaccurate extrapolation for answers.

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