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Advanced inhalation therapeutics Capsugel recently expanded its late-stage inhalation capabilities to advance dry powder inhalation (DPI) concepts through late-stage clini- cal trial and commercial production. The company has installed a new Harro Höflinger Modu-C MS encapsulation unit that offers specialized drum-dosing technology for use in DPI development projects utilizing spray-dry processing. The investment strengthens Capsugel's full-service inhalation product development capabilities, which include proprietary spray-dry processing, specialized CMC/analytical services, and encapsu- lation capacity to support development, clinical trial and commercial scale projects. Capsugel US: +1 888 783-6361 26 JUNE 2017 Inhalation Precision capsule filling capabilities Hovione offers a full range of inhalation development and manufacturing services, from pre-clinical to small commercial scales. Hovione's filling and packaging capabilities include automated precision capsule filling with 100% net weight unit verification, production of Phase I-III clinical trial material supplies and low-volume commercial supplies as well as blistering and packaging. In addition, its capabilities include composite particles formulation, carrier-based formulation, particle engineering and advanced analytical characterization. Hovione Portugal: +351 21 982 9000 Options for capsule filling With a full line of capsule filling equipment, Qualicaps offers manu- facturers a wide range of options to suit their capsule filling needs. Qualicaps' series of capsule filling equipment has a variety of capabili- ties, including unique options to fill capsules within a capsule, as well as combinations of different products within one capsule. The F40, for example, can be used to fill various types of dosage forms while main- taining a high level of accuracy of fill weights to ensure precision. Qualicaps US: +1 800 CAPSULE SPECIALSECTION FILLING & PACKAGING This section of Inhalation provides information that may be useful in research and development or manufacturing. Content is provided by the companies listed. No product endorsement or preference is intended.

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