ALKYNE REACTIONS
Acetylene derivatives (alkynes) are the back bone to the GFS organic product line. The acquisition of Farchan Laboratories (Gainsville, FL) in the mid-1990's added over 400 core alkynes to our product list.
With this came the addition of liquid ammonia chemistry as a reaction media as well as helped further expand our work in the area of Sonogashira chemistry among other palladium (Pd) catalyzed coupling reactions. The use of trimethylsilylacety- lene (TMSA, TMS Acetylene)
3
