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Bovine antibiotics
Product Active Ingredient Indications Approved Dosage
Label
Treatment
Pre-Slaughter
Withdrawal
Milk Discard
Approved
for Lactating
Cows
ADVOCIN
™
Danofloxacin
mesylate
Treatment and
control of BRD
1 dose
2mL/100lbs
multi-day
1.5mL/100lbs
1 dose only
multi-day -
2 days apart
4 days N/A No
AMPICILLIN
Ampicillin
Trihydrate
BRD 2-5mg/lb
1 per day up
to 7 days
6 days 48 hours Yes
BAYTRIL
®
100
Enrofloxacin
Treatment and
control of BRD
refer to label refer to label 28 days N/A No
CEFTIFLEX
®
Ceftiofur Sodium
Treatment of BRD
and foot rot
1-2mL/100lbs
1 per day for
3-5 days
4 days 0 days Yes
DRAXXIN
®
Tulathromycin
Treatment and
control of calf
pneumonia, and
treatment of pinkeye
1.1mL/100lbs 1 dose only 18 days N/A No
ENROFLOX
™
100
Enrofloxacin
Treatment and
control of BRD
refer to label refer to label 28 days N/A No
EXCEDE
®
Ceftiofur
Crystalline Free
Acid
Treatment of BRD 1.5mL/100lbs 1.5mL/100lbs 13 days 0 days Yes
EXCENEL
®
RTU EZ
Ceftiofur
Hydrochloride
Treatment of metritis,
BRD, and foot rot
1-2mL/100lbs
1 per day for
3-5 days
4 days 0 days Yes
MICOTIL
®
Tilmicosin Treatment of BRD 1.5-3mL/100lbs 1 dose only 42 days N/A No
NAXCEL
®
Ceftiofur Sodium
Treatment of BRD
and foot rot
1-2mL/100lbs
1 per day for
3-5 days
4 days 0 days Yes
NORFENICOL
®
Florfenicol
Treatment of BRD
and foot rot
6mL/100lbs 1 dose only
28 days IM
38 days SC
N/A No
NUFLOR
®
Florfenicol
Treatment of BRD
and foot rot
6mL/100lbs 1 dose only
28 days IM
38 days SC
N/A No
Penicillin
Penicillin G
Procaine
BRD
varies by
manufacturer
varies by
manufacturer
varies varies varies
POLYFLEX
®
Ampicillin
Trihydrate
BRD 2-5mg/lb
1 per day up
to 7 days
6 days 48 hours Yes
RESFLOR GOLD
®
Florfenicol
Flunixin
Megllumine
Treatment of BRD 6mL/100lbs 1 dose only 38 days N/A No
Tetracycline
Oxytetracycline
BRD foot rot,
metritis, pinkeye,
scours, wooden
tongue, Leptospira
pomona
varies by
manufacturer
varies by
manufacturer
varies varies varies
ZACTRAN
®
Gamithromycin Treatment of BRD 2mL/110lbs 1 dose only 35 days N/A No
ZUPREVO
™
18%
Tildipirosin
Treatment of BRD
and control of
respiratory disease
1mL/100 lbs 1 dose only 21 days N/A No
PLEASE NOTE: This chart is designed to be a comparative reference guide but is not intended to replace or be a complete source of label or package insert information for each product.
© 2019 Covetrus. All Rights Reserved. No copying without permission. Not responsible for typographical errors. Lit. No. 19EQLS250 (09/2019)
