Issue link: https://www.e-digitaleditions.com/i/1199406
32B January 2020 Tablets & Capsules JIANTAO ZHANG, YIDAN LAN, ASHISH JOSHI, AND NIGEL LANGLEY BASF Improving CoQ10 ODT formulation for increased patient compliance orally disintegrating tablets C This article discusses how an orally disintegrating tablet for- mulation for CoQ10 was developed to improve mouthfeel compared to a commercial analog. oenzyme Q10 (CoQ10) is an effective antioxidant that plays a fundamental role in cellular bioenergetics, offers cardiac health benefits, and prevents cell damage from free radicals. However, many commercial CoQ10 dietary supplements are capsule products that can be hard to swallow for geriatric patients [1]. Orally disintegrating tablets (ODTs) offer nutraceutical manufacturers a solu- tion for patients that experience dysphagia and other swallowing difficulties when taking solid oral dosage