Tablets & Capsules

TC0420

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12 April 2020 Tablets & Capsules A Federica Giatti, Massimo Malavolti, Fabriano Ferrini, and Caterina Funaro IMA Active Taste masking minitablets using a drum coater tablet coating The minitablet can be a patient-friendly dosage form for geriat- ric and pediatric patients, who may have difficulty swallowing large tablets or capsules. Minitablets can also be coated and combined to achieve multiple drug release profiles within a sin- gle dosage form. This article describes the benefits of using minitablets to create taste-masked multiparticulate oral solid dosage forms and evaluates a minitablet manufacturing process for feasibility, including tableting and pilot- and produc- tion-scale coating in a drum coater. minitablet is generally a round tablet with a flat or slightly convex face and a diameter between 1.0 and 3.0 millimeters. Minitablets are usually filled into a capsule, but they are also occasionally compressed into larger tab- lets or placed in sachets for easy administration. Minitablets combine the advantages of multipartic- ulate dosage forms with the established manufacturing techniques of tableting. Their small size gives them sev- eral advantages over traditional single-unit dosage forms, including being easier to swallow for geriatric and pediat-

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