Issue link: https://www.e-digitaleditions.com/i/1331851
Tablets & Capsules January/February 2021 31 direct torque readings can be directly correlated to accu- rate endpoint determination. T&C Vasant Shetty is head of the process technology, granulation, and tablet coating division at ACG. He has more than 25 years of pharmaceutical industrial experience in various fields, including production, process development, and engineering. Dr. Rahul Aware is manager of process technology support at ACG. He has completed his graduation in pharmacy and holds a PhD in process technology from Mumbai University. He has worked for 10 years as a granulation and drying con- sultant for various pharma, food, and chemical companies and has been with ACG for five years. For more information, con- tact ACG North America, Piscataway, NJ (908 757 3425, sales.acgna@acg-world.com). Figure 2 Comparison of calculated impeller current versus impeller direct torque (ACG 1200 L HSM) Impeller current (amperes) Time Impeller torque (newton meters) 90.0 80.0 70.0 60.0 50.0 40.0 30.0 20.0 10.0 0.0 12:15:31 12:16:21 12:17:12 12:18:02 12:18:52 12:19:42 12:20:32 12:21:22 12:22:12 12:23:03 12:23:53 12:24:43 12:25:34 12:26:23 12:27:14 12:28:04 12:28:53 12:29:44 12:33:09 12:34:00 12:34:49 4,000 3,500 3,000 2,500 2,000 1,500 1,000 500 0 Dry mixing Spraying Wet mixing Impeller current Impeller torque