Tablets Capsules


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34 March/April 2021 Tablets & Capsules A survey of what's available multilayer tableting R&D bilayer tablet press Eliz-200 L high-tonnage R&D tablet press produces up to 19,800 bilayer tablets per hour and offers 10 kilonewtons of pre-compression force and up to 50 kilonewtons of main compression force. Tablet press' turret can be configured with 9 stations using D tooling, 11 stations using B tooling, and 10 stations of D and B tooling. Adjustable upper punch overload system prevents tool damage, and a lower punch pull-down cam reduces tablet weight deviation. Features include automatic first- layer sampling, pre- and main compression load cells, GMP wear-coated contact parts, a hardened-steel wear plate and die table, and a large-capacity motor that provides uninterrupted motion. Elizabeth, McKeesport, PA 412 829 7700 R&D Bilayer tablet press Piccola bilayer tablet press for R&D and pilot production comes with a TSM or EU turret to accommodate B, D, and B and D tooling. GMP-compliant unit pro- duces 45,000 to 51,000 tablets per hour, with a maximum force for both layers of 80 kilonewtons. Company's Director software for data acquisition and analysis comes standard and generates compaction profiles using as little as 300 grams of material. Breakdown and retooling takes just 30 minutes. Other features include dual-paddle feeders, an automatic adjustment feature for the lower rolls and weight cams, and an ejection force transducer. SMI, Bethlehem, PA 908 534 1500 Bilayer tablet press C 300 high-speed tablet press features interchangeable turrets for single- and bilayer tableting and a layer-sampling and rejection mechanism that ensures each layer meets the target weight. Like the company's other C-series presses, the C 300 has fully computerized compaction force control for automatic weight con- trol as well as monitoring and adjustment of main compression, pre-compression, and ejection force. Unit's pre- and main compression rolls have equal capacity, which is useful for tableting difficult formulations. Options include a three-paddle feeder and a multiple-unit pellet-feeder for modified-release products. Company also offers the Cadpress IIA, IV, and Expert 1 bilayer tablet presses. CMC Machinery, Princeton, NJ 609 720 9800

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