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Pharmaceutical Technology APIs, EXCIPIENTS, AND MANUFACTURING eBOOK 2021 45 components outside of the preset limits. Addition- ally, the toolbox can fit the RTD model to a series of experimental data to calculate RTD parameters. The current version of the RTD based toolbox has two modules. For prediction of the outlet con- centration, the inputs are RTD model parameters and real-time inlet concentration. The toolbox will compute the convolution of the RTD model with the inlet concentration and provide real- time predictions of the outlet concentrations of the product. Figure 1 shows the general workf low of this module. Figure 1. Workflow of stand-alone self-contained tool. Inlet concentration Convolution Calculated outlet concentration Rejection signal Comparison Pulse response RTD parameters Figure 2. Prediction module workflow. FIGURES COURTESY OF THE AUTHOR.