Cannabis Patient Care - November 2021

Cannabis Patient Care November Issue

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15 research focus october/november 2021 | cannabis patient care as antitumor agents," Oncotarget. DOI: 10.1016/j.jsps.2019.01.005. Retrieved from Cannabis-as-Baram-Peled/ca3a543b372e5474439fbfc4bd5cbc4f41e904cf (2019). (6) J. Glogauer and J. Blay, "Cannabinoids, Their Cellular Receptors, and Effects on the Invasive Phenotype of Carcinoma and Metastasis" Cancer Reports. DOI: 10.1002/cnr2.1475. Retrieved from (2021). (7) Treatment Side Effects (2021, Mar 29). Retrieved from (8) J. Aviram, et al, "Short-Term Medical Cannabis Treatment Regimens Produced Beneficial Effects among Palliative Cancer Patients," Pharmaceuticals. DOI: 10.3390/ph13120435. Retrieved from www. (2020). (9) M. Weiss, et al "A survey of cannabis use for symptom palliation in breast cancer patients by age and stage," J. of Clinical Oncology. Retrieved from (2020). (10) A.I. Fraguas-Sánchez, A. Fernández-Carballido, R. Simancas-Herbada, C. Martin- Sabroso, and A.I. Torres-Suárez, "CBD loaded microparticles as a potential formulation to improve paclitaxel and doxorubicin-based chemotherapy in breast cancer," International Journal of Pharmaceutics. DOI: 10.1016/j. ijpharm.2019.118916. Retrieved from (2019). (11) M.M. Caffarel, C. Andradas, E. Pérez-Gómez, M. Guzmán, and C. Sánchez, "Cannabinoids: A new hope for breast cancer therapy?" Cancer Treatment Reviews. DOI: 10.1016/j.ctrv.2012.06.005. Retrieved from www.semanticscholar. org/paper/Cannabinoids%3A-a-new-hope-for-breast-cancer-therapy- Caffarel-Andradas/998e07defe9c75215c34acae8118718f0e5bf55f (2012). (12) M. Caffarel, et al, "D9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation," Cancer Research. DOI: 10.1158/0008-5472.CAN-05-4566. Retrieved from cancerres. (2006). (13) Breast Cancer Ploidy and Cell Proliferation. (2019, Sep 20) American Cancer Society. Retrieved from understanding-a-breast-cancer-diagnosis/ploidy-and-cell-proliferation.html. (14) L. Dobovišek, et al, "Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment," Cancers. DOI: 10.3390/cancers12030525. Retrieved from https://www. (2020). (15) D. Ladin, et al, "Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents," Frontiers in Pharmacology. DOI: 10.3389/ fphar.2016.00361. Retrieved from articles/PMC5054289/pdf/fphar-07-00361.pdf (2016). (16) M. Elbaz, et al, "Modulation of the Tumor Microenvironment and Inhibition of EGF/EGFR Pathway; Novel Anti-tumor Mechanisms Of Cannabidiol In Breast Cancer," Molecular Oncology. DOI: 10.1016/j. molonc.2014.12.010. Retrieved from of-the-tumor-microenvironment-and/25660577 (2015). (17) R. Murase, et al, "Targeting multiple cannabinoid anti-tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer," British J. of Pharmacology. DOI:10.1111/bph.12803. Retrieved from (2014). (18) Apoptosis. (n.d.) National Cancer Institute. Retrieved from (19) A. Tomko, et al, "Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer," Frontiers in Pharmacology. DOI: 10.3389/fphar.2019.01124. Retrieved from (2019). (20) A. Sultan, M. Marie, and S. Sheweita, "Novel mechanism of cannabidiol- induced apoptosis in breast cancer cell lines," The Breast. DOI: 10.1016/j. breast.2018.06.009. Retrieved from (2018). (21) A. Shrivastava, et al, "Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy," Mol. Cancer Ther. DOI: 10.1158/1535-7163.MCT-10- 1100. Retrieved from (2011). (22) Angiogenesis. (n.d.) National Cancer Institute. Retrieved from (23) P. Picardi, E. Ciaglia, M. Proto, and S. Pisanti, "Anandamide inhibits breast tumor-induced angiogenesis," Transl. Med. UniSa. Retrieved from elea. Anandamide_inhibits_breast_tumor_induced_angiogenesis.pdf (2014). (24) N. Farsandaj, M. Ghahremani, and S. Ostad, "Role of cannabinoid and vanilloid receptors in invasion of human breast carcinoma cells," J. Environ. Pathol. Toxicol. Oncol. DOI: 10.1615/jenvironpatholtoxicoloncol.2013005859. Retrieved from (2012). (25) P. Friedl and K. Wolf, "Tumour-cell invasion and migration: diversity and escape mechanisms," Nature Reviews Cancer. Retrieved from (2003). (26) S. Takeda, et al, "Cannabidiolic acid, a major cannabinoid in fiber- type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration," Toxicology Letters. DOI: 10.1016/j.toxlet.2012.08.029. Retrieved from (2012). (27) S. Takeda, et al, "D9-Tetrahydrocannabinol enhances MCF-7 cell proliferation via cannabinoid receptor-independent signaling," Toxicology. DOI: 10.1016/j.tox.2007.12.019. Retrieved from www.sciencedirect. com/science/article/abs/pii/S0300483X07008566 (2008). (28) R. McKallip, M. Nagarkatti, and P. Nagarkatti, "∆-9-Tetrahydrocannabinol Enhances Breast Cancer Growth and Metastasis by Suppression of the Antitumor Immune Response," J. Immunol. DOI: 10.4049/jimmunol.174.6.3281. Retrieved from (2005). (29) B. Dariš, M. Verboten, Z. Knez, and P. Ferk, "Cannabinoids in cancer treatment: Therapeutic potential and legislation," Bosnian J. of Basic Medical Sciences. DOI: 10.17305/bjbms.2018.3532. Retrieved from www.ncbi. (2018). (30) T. Kisková, et al, Retrieved from Future Aspects for Cannabinoids in Breast Cancer Therapy. International J of Molecular Sciences. DOI: 10.3390/ijms20071673. Retrieved from pmc/articles/PMC6479799/pdf/ijms-20-01673.pdf (2019). About the author RUTH FISHER, PHD, is a systems design researcher and an- alyst. She analyzes markets to determine how environments shape outcomes. She is co-founder of CannDynamics, Inc., and author of The Medical Cannabis Primer and Winning the Hardware-Software Game: Using Game Theory to Optimize the Pace of New Technology Adoption. Dr. Fisher has worked in the technology and healthcare sectors on behalf of tech- nology companies, early-stage researchers, physicians, and technology start-ups.

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