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Psychedelics: New Frontiers in Alternative Medicine | vol. 5 no. 5 cannabissciencetech.com 16 feature / processing/manufacturing orientation, our team is focused on deliv- ering six key benefits for our psilocybin offerings: 1. Convenience: The product should be convenient to use, convenient to buy, convenient to carry, and convenient to store. 2. Assured dosing: The product should be delivered in an as- sured dose including a microdose option. Currently, consumers have little idea as to what dose they require or what dose they are taking. Reliable dosing helps insure a consistent and positive experience. 3. Bioavailability: Consumers prefer a functional product and a faster onset time via improved bioavail- ability, which makes the prod- uct more functional and far more appealing. 4. Safety: Consumers want to know that what they are ingesting is safe. That's why comprehensive, independent third-party labora- tory testing for purity and poten- cy on every batch is important for widespread adoption. 5. Palatability: The product should taste and smell good. Since mushrooms typically do not have great flavor or aroma, a better tasting product with a better aro- ma will improve the customer ex- perience markedly and will deliv- er more sales. 6. Affordability: Making the product affordable extends the market to a larger addressable and acces- sible audience. Quite simply, that means more consumer trial and adoption plus greater sales. Af- fordability will make it easier for people to integrate psilocybin into their daily lives. This means frequency of usage, an objective that any repeat purchase product is seeking. In Oregon, we are developing a spore- to-sale model for psilocybin, mindful of our goals of providing our six core ben- efits. Here is an outline of the areas we believe are critical in creating an infra- structure for building the space right. Our intent is to develop a lightweight, non-capital-intensive, portable mod- el that is replicable globally as psilocy- bin becomes legal from state to state and from country to country. Legal, Regulatory, and Compliance It is essential to create a psilocybin product within the legal and regulatory environment of the states and countries in which we plan to operate. Laws and regulations do vary by jurisdiction, so it is essential to find legal experts in that jurisdiction. Fortunately, there are indi- vidual lawyers and law firms well-versed in psychedelics law that can help. Some attorneys who operate within this special- ty do cover multiple jurisdictions. Others will only cover one jurisdiction. Our plan is to interview extensively and then hire exceptional lawyers before proceeding to build in any place we expect to operate. Genetics The right genetics will be essential to create unique, high-quality psilocybin offerings. We have access to a library of psilocybe cubensis sub-species curated from unique regions throughout the world. Most of the strains are 7 th genera- tion with low heterozygosity (or genetic deviation). These genetics have been stored carefully using swab prints, slants, and petri dishes. This premium library contains many high yielding strains that have been isolated for strength, resis- tance to contamination, and psilocybin or psilocin potency. Many of our genetics also maintain fast colonization rates over multiple flushes. Culture Maintenance Set-Up and Lifecycle Management Setting up a functional laboratory environ- ment that controls plating and cultivation is a challenging task. The laboratory set-up must consider state regulated compliance, building codes, and many approvals, most likely from multiple government agencies. Once these hurdles have been cleared, set- ting up a proper laboratory environment requires the following: Lifestyle Architecture This must involve well planned proce- dures for spore transfers to agar plates for isolations, as well as mycelium to live culture growth transfers. There must be long-term storage plans and capabilities to maintain proper genetic health. In addition, appropriate infrastructure must be designed and built to house, maintain, and ensure non-contamination in near zero temperatures. Specialized cryogenic expertise is a necessity. Humidity must be controlled as well and processing systems must have minimal touch time to avoid unwanted exposure risks. Isolation Procedures Strict isolation procedures are critical to a high quality and consistent result. They include: • Agar core to agar plate • Agar core sample to live culture • Spore printing to glass, fill, and swab • Tissue sampling to live culture and cryogenic storage Sterilization and Pasteurization Procedures One cannot ignore the importance of sterilization and pasteurization. These procedures are vital: • Live culture isolation • Spawn media