11 Fall/Winter 2022 | Equine Solutions
EPM Suspect Case Immunodiagnostics
Blood serum (+)
CSF (+)
Treat
Re-evaluate
(30 days)
≠ EPM
Correlates with EPM
Blood serum (-)
EPM ruled out
Differential 2
?
Differential 3
?
CSF (-)
EPM ruled out
Differential 2
?
Differential 3
?
FIGURE 1: WHAT IS A PROPER EPM DIAGNOSTIC WORKUP?
Completing a thorough
physical and neurologic
exam is a critical
first step in the EPM
diagnostic process.
Image courtesy of Merck Animal Health.
If EPM rises to the top of your list of differentials after a thorough physical and neurological exam, antibody testing should
be used to further differentiate EPM from other neurological diseases. Intrathecal antibody production is the most accurate
way to support an EPM diagnosis, while blood is useful for screening.
