Animal Health Solution - a Henry Schein Animal Health magazine for veterinary professionals
Issue link: https://www.e-digitaleditions.com/i/1492756
All trademarks are registered trademarks or trademarks of Pegasus Laboratories, Inc. © 2023 PRN Pharmacal, Inc. All rights reserved. TREATING URINARY INCONTINENCE JUST GOT EASY Find prescribing and dosing information at PROIN-ER.com IMPORTANT SAFETY INFORMATION: For oral use in dogs only. Not for human use. Keep out of reach of children. If accidentally ingested by humans, contact a physician immediately. The most commonly reported side effects were vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (fl ushing or bright pink). Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported. In some cases death, including euthanasia has been reported. Sudden death was sometimes preceded by vocalization or collapse. Instances of dogs chewing through closed vials of PROIN ® and eating the vial contents have been reported, in some cases resulting in over- dose. Keep the product in a secured storage area out of the reach of pets in order to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommend- ed dosage of PROIN ® Chewable Tablets or PROIN ER ™ tablets. Contact your veterinarian immediately if the dog ingests more tablets than prescribed or if other pets ingest PROIN Chewable tablets or PROIN ER tablets. PROIN and PROIN ER may cause elevated blood pressure and should be used with caution in dogs with pre-existing heart disease, high blood pressure, liver disease, kidney insuffi ciency, diabetes, glaucoma, and other conditions associated with high blood pressure. Dogs may transition from PROIN Chewable Tablets to PROIN ER without a break in ad- ministration. However, do not alternate PROIN ER with PROIN Chewable Tablets because the effectiveness and safety of interchangeable use have not been evaluated. The safe use of PROIN and PROIN ER in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated. Contact your veterinarian if you notice restlessness or irritability, loss of appetite, the incontinence persists or worsens, or any other unusual signs. See prescribing information for complete details regarding adverse events, warning and precautions or visit prnpharmacal.com. Your canine patients can now can get the same, e ective treatment for urinary incontinence (UI) as PROIN® in a convenient, once-a-day dose with PROIN ER – the ONLY FDA-approved treatment of UI due to urethral sphincter hypotonus in a convenient once-a-day tablet. The controlled release mechanism in our patented extended-release technology maintains steady absorption throughout the day. And the once-a-day dosing and delicious liver avoring help improve compliance. Now it only takes one Special PROIN ER ™ O er: Buy 4 and get a FREE gift. Ask your Covetrus Veterinary for more details. O er valid 3/1 through 4/30.