7 March 2023 | Product and Promotions Guide
E
quine wound management presents many
problems for the practicing veterinarian.
1
Microbial
contamination and biofilm growth are common and
can prevent healing. Tensional forces on the wound can
lead to wound expansion. Wound contraction is often
slow, increasing the risk of developing proud flesh which
slows or stalls healing and necessitates debridement.
The challenges are exacerbated in the case of distal
limb wounds which contract more slowly (0.2 mm/day)
and re-epithelialize more slowly (0.09 mm/day) than
truncal wounds (contraction-0.8 mm/day). Slow healing
and chronic inflammation can lead to weak and poorly
perfused tissue, proud flesh, and potentially scarring. An
ideal wound healing product would promote rapid healing
and mitigate these issues.
Nitric oxide: A key regulator of the natural
healing process
Nitric oxide is an endogenous gas that serves as a biologic messenger in many
physiological processes
2
, most notably, wound healing.
3
Nitric oxide is produced
by enzymes acting upon the amino acid L-arginine. Nitric oxide as a topical
treatment has shown tremendous promise across species in everything from
human and equine to companion animal and exotic applications.
4
NITRIC OXIDE:
May reduce the occurrence of proud flesh
in equine distal limb wounds
Mitigates microbial infection in all wound types
Shortens overall time to wound closure,
greatly improving healing outcomes
