Equine & Livestock Product & Promotions Guide

June 2023

Animal Health Solution - a Henry Schein Animal Health magazine for veterinary professionals

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7 June 2023 | Product and Promotions Guide W hen it comes to mastitis treatment, many factors impact its effectiveness. While we know some of those variables, there are many unknowns. Understanding known and unknown variables will help uncover the best treatment decisions for each cow. Dr. Pamela Ruegg, professor of large animal clinical sciences at the Michigan State University College of Veterinary Medicine, recently summarized research-based evidence related to clinical mastitis treatment. 1 Research findings over many years and under a variety of management practices provide insights into what we know about mastitis and the effectiveness of treatment. What we do know What we do know Mastitis treatment products have similar efficacy. With rare exceptions, researchers report few significant differences between approved intramammary (IMM) antibiotics in achieving bacteriological or clinical cure rates. Therefore, producers may consider other product characteristics to make treatment decisions. These might include treatment duration and total time that the milk must be withheld, slaughter withdrawal time, product cost and other considerations. Normal milk is not a reliable indicator of effectiveness. Producers sometimes judge treatment success based on milk returning to a normal appearance. However, this outcome is not a good indicator of therapeutic success. A bacteriological cure – or the elimination of bacteria – often occurs well before milk returns to normal. Even with effective treatment, inflammation can remain in the quarter and cause abnormal milk for several days after bacteria have been eliminated. Don't forget the difference between cow-level and quarter-level somatic cell count (SCC). While quarter-level SCC is a reasonably accurate metric of treatment success, cow-level SCC is an "average" of four quarters – so cow-level SCC is a poorly sensitive way to assess treatment success in any one of those quarters.

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