Protect canine synovial joints
before signifi cant damage occurs.
Prescribe FDA-approved Adequan
®
Canine (polysulfated glycosaminoglycan)
at the fi rst clinical signs of canine osteoarthritis (OA).
Using a disease-modifying osteoarthritis drug
(DMOAD) can prevent further joint damage and
may help:
1
• Restore joint lubrication
• Relieve infl ammation
• Renew the building blocks
of healthy cartilage
Adequan
®
Canine polysulfated glycosaminoglycan (PSGAG)
Indications and Usage Adequan Canine is recommended for intramuscular injection for the control of signs associated with non-infectious
degenerative and/or traumatic arthritis of canine synovial joints. IMPORTANT SAFETY INFORMATION Adequan Canine should not be used
in dogs who are hypersensitive to polysulfated glycosaminoglycan (PSGAG) or who have a known or suspected bleeding disorder. It should be
used with caution in dogs with renal or hepatic impairment. Adverse reactions in clinical studies (transient pain at injection site, transient diarrhea,
and abnormal bleeding) were mild and self-limiting. In post approval experience, death has been reported in some cases; vomiting, anorexia,
depression/lethargy and diarrhea have also been reported. The safe use of PSGAG in breeding, pregnant or lactating dogs has not been evaluated.
Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian. For additional safety information, please see Full
Prescribing Information at adequancanine.com and view the Brief Summary adjacent to this ad.
1. Adequan
®
Canine (polysulfated glycosaminoglycan), Package Insert. American Regent, Inc.
Adequan and the Dog Head design are registered trademarks of American Regent, Inc. © 2023, American Regent, Inc. PP-AC-US-0617
Visit adequancanine.com to discover if
Adequan Canine is right for your patients.
How Adequan Canine works
within the canine synovial joints:
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Inhibits
Catabolic
Enzymes
Reduces
Infl ammatory
Mediators
Enhances
Anabolic
Enzymes
The specifi c mechanism of action of
Adequan in canine joints is not known.
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To order, contact your Covetrus representative at 855.724.3461 or visit northamerica.covetrus.com
