BioPharm
I N T E R N AT I O N A L
eBook
T h e S ci e n ce & B usi n e ss o f B i o p h a r m a ce u t i c a ls
FOUNDER
Mike Hennessy Sr
1960 - 2021
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Contents
EDITORIAL
Vice President, Content Alicia Bigica ABigica@mjhlifesciences.com
Associate Editorial Director Felicity Thomas FThomas@mjhlifesciences.com
Lead Editor Susan Haigney SHaigney@mjhlifesciences.com
Science Editor Feliza Mirasol FMirasol@mjhlifesciences.com
Editor Patrick Lavery PLavery@mjhlifesciences.com
Contributing editors
Cynthia A. Challener
Design and Production
Creative Director Robert McGarr rmcgarr@mjhlifesciences.com
Senior Art Director Kristen Morabito kmorabito@mjhlifesciences.com
Print and Circulation Director Jonathan Severn jsevern@mjhassoc.com
Production Manager Charlton Prince cprince@mjhlifesciences.com
Print Production Coordinator Amber Immordino ammordino@mjhassoc.com
CUSTOM CONTENT
Director Robert Alaburda
Managing Editor Jeanne Linke Northrop
Senior Editor Megan Manzano
Senior Editor Shannon Stolz
ADVERTISING
National Sales Manager Scott Vail SVail@mjhlifesciences.com
Sales Manager Joel Kern JKern@mjhlifesciences.com
European Sales Manager Linda Hewitt LHewitt@mjhlifesciences.com
European Senior Sales Executive Stephen Cleland
SCleland@mjhlifesciences.com
Director, Industry Relations and Strategic Partnerships Chris Spivey
CSpivey@mjhlifesciences.com
MJH LIFE SCIENCES
®
President & CEO Mike Hennessy Jr
Chief Financial Officer Neil Glasser, CPA/CFE
Chief Operating Officer Beth Buehler
Chief Data Officer Terric Townsend
Executive Vice President, Global Medical Affairs
& Corporate Development Joe Petroziello
Executive Vice President, Healthcare Brian Haug
Senior Vice President, Content Silas Inman
Senior Vice President, Human Resources
& Administration Shari Lundenberg
Senior Vice President, Mergers & Acquisitions,
Strategic Innovation Phil Talamo
Executive Creative Director Jeff Brown
Manufacturing and Facilities
eBook November 2024
Cover: Bos Amico – Stock.Adobe.com
BIOPROCESSING
A Step Closer to Closure in Bioprocessing
Sarah Le Merdy and Christophe Dufossé
As biopharma anticipates the "Facility of the Future,"
a definition of what closed processing is, and
quantification of its value, can be helpful information. 4
MANUFACTURING
The Patient-Centric Manufacturing Model
Susan Haigney
Jason Bock, co-founder and CEO of CTMC,
discusses the industry impact and
manufacture of patient-centered medicines. 11
OUTSOURCING
How Modularization and Digital Delivery
are Transforming Pharma Manufacturing
Jordan Ulrich and Dana Tilley
Modular and replication strategies are being
utilized to meet growing demand for CDMO facilities. 14
FACILITIES
Quality Pitfalls of Aging
Facilities and Equipment
Susan Haigney
Operating in an aging facility and/or
utilizing outdated equipment may lead
to drug shortages and high operating costs. 18
ANALYTICS
Extracellular Vesicles and Fluorescence
Excitation-Emission Matrix Spectroscopy
Lyufei Chen
Fluorescence spectroscopy offers
unique advantages for characterizing EVs. 22
AD INDEX 26
www.biopharminternational.com Manufacturing and Facilities eBook November 2024 BioPharm International
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