Inhalation

INH0225

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22 February 2025 Inhalation Powder dosing and device assembly technologies 3P innovation is a global leader in powder dispens- ing technologies and in filling and sealing automation equipment. Our propriety gravimetric technology, Fill2Weight, can enable users to dose accurately and quickly to sub-1 mg levels of the most challenging and sensitive powders. Based out of the UK, we have a long history of supplying custom automation equipment to enabling filling and sealing of innovative delivery devices for both orally and nasally inhaled powders. Our approach to custom automation can de-risk the manufacturing process for our customers, from early- stage clinical trials through full commercial scale. 3P innovation UK: +44 1926 408933 enquiries@3pinnovation.com www.3pinnovation.com Inhaled and nasal drug delivery systems RxPack is a global leader in pharmaceutical dispens- ing solutions and inhaled nasal drug delivery systems. Specializing in pMDIs, RxPack offers a comprehen- sive valve portfolio for solutions and suspensions, for single or double-stage filling. e company supports its customers in navigating complex product devel- opment changes and the transition from the existing propellants to the new HFA 152a and HFA1234ze gases. RxPack partners with Coster's Machinery Division for the provision of lab-scale and high- speed filling lines. RxPack S.r.l. Italy: +39 034118960 info@rxpack.it www.rxpack.eu Plasma process for treating MDI canisters H&T Presspart offers a unique plasma process—man- ufactured under license from Portal Medical Ltd—for treating the internal surfaces of metered dose inhaler (MDI) canisters, which can help ensure the active drug content does not stick to the canister wall. is fluorocarbon polymerization (FCP) plasma treatment process can improve the surface energy performance of an MDI canister, which can enhance drug stability in formulations where interactions with the alumin- ium substrate can lead to product degradation and reduced shelf life. H&T Presspart UK: +44 1254 582233 blackburn@presspart.com www.presspart.com Dry powder inhalation capsule portfolio Lonza's Capsugel ® Zephyr™ dry powder inhalation (DPI) capsule portfolio is a comprehensive capsule product offering, featuring customized DPI capsules and dedicated equipment in place for efficient, phase- appropriate capsule filling. e Zephyr DPI portfolio addresses the need for highly customized solutions for pulmonary route delivery methods and is supported by Lonza's inhalation and drug development and par- ticle engineering capabilities. is integrated product and service offering can enable consistent and optimal release performance for inhalation drugs. Lonza Capsules & Health Ingredients US: +1 888 783-6361 www.lonza.com

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