Tablets & Capsules Solid Dosage Sourcebook June 2014 73
Nippon Soda Co., Ltd. ("NISSO") is a research and development focused chemical company supplying products worldwide to
the pharmaceutical, food, agrochemical, paper and auto industries, among others. For over 40 years, Nisso has manufactured
the highest quality hydroxypropyl cellulose (HPC) to meet the strictest demands of the pharmaceutical and food markets. NISSO
HPC is the leading pharmaceutical binder in Japan and is used in over 3,000 pharmaceutical products
worldwide.
Serving the pharmaceutical and
nutritional supplement tableting market,
examples of NISSO HPC applications
are as follows:
• Wet granulation binder to give
excellent tablet properties for
hardness and friability
• Dry binder to give excellent tablet
strength without compromising the
disintegration using special low
viscosity grades
• Extended release matrix using high
viscosity grades
• Solubility enhancement via hot melt
extrusion, spray drying, ball milling
and solvent evaporation techniques
• Film forming to improve elasticity and
adhesion of coatings to tablets
Nisso America, Inc.
88 Pine Street 14th Fl
New York, NY 10005
Tel: 212 490 0350
800 490 0351
FAX: 212 972 9361
Email: info@nissoamerica.com
Website: www.nissoexcipients.com
Corporate Description
Markets Served
Nisso has R&D and production facilities
for HPC in Niigata Prefecture, Japan.
Our Headquarters is in Tokyo, with
subsidiaries for sales, marketing and
technical support in New York, U.S.A.
and Dusseldorf, Germany.
Facilities
NISSO HPC: NISSO HPC is a cellulose-derived polymer that combines water and
organic solvent solubility. Manufacturing of NISSO HPC was started in 1967, and it
was listed in the Japanese Pharmacopeia in 1971. Since then, NISSO HPC has
become widely used as high performance versatile pharmaceutical excipient in oral
solid dosage forms, topical hydrocolloids, and fast-dissolving films. NISSO HPC is
available in a range of grades and particles sizes including special low viscosity
grades. For food use, Nisso supplies CELNY brand of HPC.
Major Products or Services
Nisso America, Inc.
Please visit www.nissoexcipients.com for more information.
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