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Industry news 8 Calendar 46 Supplier news 46 TABLETS & CAPSULES tabletting Making better tablets: A QbD approach 10 Michael Gamlen and Joe Domingue Continuous tablet manufacturing: Faster development and greater efficiency 18 David Ross Issue focus: Tabletting 24 I Holland's TSAR-Predict forecasts faster fixes for sticking problems 29 AAPS preview 30 Liquid capsule filling: A survey of what's available 32 Hard work on softgels pays off at Forever Living 34 Gums, films & powders: A survey of what's available 38 Pack Expo-Pharma Expo preview 39 Eye on Excipients 41 Irwin B. Silverstein and Jim Morris Back Page 48 Andre Petric Tablets & Capsules (ISSN 1549-9928 print; ISSN 1938-9159 online) is published eight times a year in January, March, April, May, July, September, October, and November by CSC Publishing, Inc., 1155 Northland Drive, Saint Paul, MN 55120. Periodicals postage paid at Saint Paul, MN, and additional mailing office. POSTMASTER: Send address changes to Tablets & Capsules, 1155 Northland Drive, Saint Paul, MN 55120. departments w w w . t a b l e t s c a p s u l e s . c o m September 2014 Volume 12 Number 6 also in this issue 'Tis the season for trade sh o w s a n d i n d u s t r y conferences, and the staff of Tablets & Capsules is gearing up to attend and exhibit. Our visits begin September 30 with TechnoPharm-Powtech in Nuremberg, Germany, followed by CPhI in Paris, France, the following week. In early November, some of us head to Chicago, IL, for Pack Expo-Pharma Expo, while others travel to San Diego, CA, for the AAPS annual conference and expo. Please look us up. At AAPS, our booth number is 3318. Website: www.tabletscap sules.com. E-mail: tc@cscpub.com.