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48 March 2016 Tablets & Capsules other sites that have received this third-party GMP certification, which as issued by SGS ICS France. Novasep adds two labs to US facility LYON, FRANCE—Novasep, a contract manufacturer, is building a new synthesis laboratory and a kilo- scale laboratory in its Boothwyn, PA facility. The additions will expand the company's chemistry and purification services and enable it to produce syn- thetic molecules needed for biological testing and preclinical trials. The labs, slated for completion in May, will include 50-liter reactors, cryogenic capabilities, chromatography pro- cesses, and analytical tools for process R&D. Study by Foster Delivery Science, U of Texas shows value of ultrafiltration PUTNAM, CT—A study by Foster Delivery Science and the University of Texas-Austin's School of Pharmacy shows that combining ultrafiltration with hot-melt extrusion reduced drug development time because it increased the speed of screening amorphous solid dispersions. Such formulations are used to improve the bioavailability APIs in oral dosage forms. According the the authors, ultrafiltration helps accelerate measurement of free API concentrations in these formulations compared to other technologies. PTI affiliate opens in Switzerland SAINT-PREX, SWITZERLAND— CCIT, an analytical leak detection lab- oratory affiliated with US-based PTI Inspection Systems, opened a facility here. Its techniques include vacuum- decay inspection, high-voltage leak detection, and airborne ultrasound technology. Hermes offers hot-melt coating for pharmaceuticals PULLACH, GERMANY—Hermes Pharma, a contract research and manu- facturing firm, has added hot-melt coating capability. The technique, common in the food industry, has already been used to mask the sour and metallic taste of an API, as well as its sulfuric smell. Netzsch appoints CMG EXTON, PA—Netzsch Premier Technologies, a manufacturer of wet and dry grinding systems and disper- sion equipment, named CMG Sales, Lake Zurich, IL, as its new sales repre- sentative for the Midwest region. FreeThink relocates BRANFORD, CT—FreeThink Technologies, which offers accelerated shelf-life and stability determinations for pharmaceuticals and dietary sup- plements, has moved. Its new address is 35 Northeast Industrial Road, Branford, CT 06405. Catalent to open clinical supply facility in Japan SOMERSET, NJ—Catalent is con- structing a 200,000-square-foot clini- cal supply facility in Kakegawa, Japan. The site will provide project manage- ment, comparator sourcing, secondary packaging and labeling, clinical stor- age, distribution, and drug return and destruction. It's slated to open midyear. people news David Simmons, chairman and chief executive officer at PPD, Wilmington, NC, was elected chair- man of the Association of Clinical Research Organization (ACRO), Washington, DC. John Hubbard, president and chief executive officer at Bioclinica, Doylestown, PA, was named ACRO's vice chairman. Robert Diehl was named director of quality and regulatory compliance at Foster Delivery Science, Putnam, CT, which specializes in using hot- melt extrusion to improve API solubil- ity. He previously held senior quality and analytical positions at Patheon and Watson Laboratories. Patheon, Durham, NC, appointed Gilles Cottier president of the pharma- ceutical development services (PDS) division. Cottier was president of Sigma-Aldrich Fine Chemicals' com- mercial unit in St. Louis, MO. His appointment allows Michael Lehmann, who led both the PDS and sales and marketing divisions, to focus on the latter. Greenville, NC, and Metrics' cus- tomers will be able to scale up more easily and without a site transfer. The plans also call for more than 10 analyt- ical labs and formulation development suites and a new visitor and staff administration center. AAI-CML adds oral solid dosage equipment, work shift to boost capacity WILMINGTON, NC—AAIPharma Services and Cambridge Major Labo- ratories (AAI-CML), a contract manu- facturer and developer has added equip- ment to its facility here that expands the company's capacity to manufacture oral solid dosage forms. The new equipment includes a coater for its fluid-bed dryer and high-shear mixer, an extruder- spheronizer, and a Bosch KKE 1700 capsule checkweigher. The new equip- ment and the addition of a second shift increases the company's solid dosage manufacturing capacity by about 35 percent. Colorcon buys pharma sugar-sphere business from Paulaur HARLEYSVILLE, PA—Colorcon acquired the pharmaceutical sugar- sphere product line from Paulaur, Cranbury, NJ, which is exiting the pharmaceutical sector to focus on con- fectionaries. The addition comple- ments Colorcon's Suglets product line. The spheres, also called seeds or pel- lets, can also be made from other excipients and are used to make multi- particulate dosage forms. See the arti- cle "Starter pellets: Materials, manufac- turing methods, and applications" in the July 2015 issue of Tablets & Capsules. Ashland's Kentucky site receives ExciPact certification CALVERT CITY, KY—Ashland Specialty Ingredients ISP Chemicals received ExciPact certification of its site here. The first US facility to receive ExciPact certification, the Calvert City site manufactures and packages polyvinyl pyrrolidone (PVP), also known as povidone, and poly- vinyl polypyrrolidone (PVPP), also known as crospovidone. PVP is used in film coatings and as binder in tablets, and PVPP serves as a binder and disintegrant. The facility joins 25