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Tablets & Capsules July 2016 11 I effervescent products Effervescent technology for today's pharmaceuticals and dietary supplements Allen H. Rau Tower Laboratories Effervescence is an underused formulation approach that offers functional and consumer advantages over conventional products in the pharmaceutical, dietary supplement, and other market segments. While the basic chemistry and process technology used to make effervescent products is not new, their complexity requires special formulation and manufacturing techniques. This article discusses the important factors to consider. s there anyone over 40 who doesn't recognize "Plop, plop, fizz, fizz. Oh, what a relief it is"? That jingle—used in Alka-Seltzer commercials in the 1970s—is not only recognized as one of the most memorable advertising lines ever, but it also neatly conveys the essence of effer- vescence. Drop two tablets into water. Watch them fizz as they disperse the active ingredients. Get quick relief. Likewise, many of today's marketers realize that the aesthetic and functional benefits of effervescent tablets