Tablets & Capsules

TC0118

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Tablets & Capsules January 2018 31 A survey of what's available granulation & drying Granulators/high-shear mixers Sejong granulators/high-shear mixers range from SM-5 pilot-scale unit that handles 1- to 5-liter batches to SM-600 unit that processes 600-liter batches. Mixers use bottom impeller and side-mounted variable-speed chopper. They also include easy-to-use PLC. Options include automatic or manual spray system, jacketed vessel, ATEX-rated explo- sion-proof motors, automatic CIP system, and agitator/ impeller lifting system. Company also offers technical ser- vice and spare parts. Key International, Cranbury, NJ. Tel. 609 619 3685 www.keyinternational.com Twin-screw extruder ZSK MegaLab twin-screw extruder for hot-melt and wet extrusion produces batches of 200 grams or less; maximum throughput is 40 kilograms per hour. Plug-and-play unit has 1.55 ratio of outer screw diameter to inner screw diameter to ease scale-up. Self-wiping twin screws can be arranged in variety of configurations, enabling you to control residence time and particle size distribution. Extruder's thin shafts with deep cuts allow you to fill up screw channel in order to pre- vent over-torquing shaft, minimize product temperature, and prevent API degradation. Unit integrates with compa- ny's PH line of loss-in-weight feeders and refill systems. Coperion K-Tron, Sewell, NJ. Tel. 856 589 0500 www.coperion.com Continuous granulator-dryer Granuformer continuous granulator-dryer produces granula- tions with particle size distributions equivalent to or better than those produced by fluid-bed or high-shear mixers. Using twin-screw extruder and binder, machine kneads and blends powders into uniform material. Material then enters spiral dryer that removes moisture using heated air. Final granules are porous, free of major agglomerations or over- sized particles, and ready for compression. Granulator-dryer supports drug development and commercial production, eliminating scale-up. Freund-Vector, Marion, IA. Tel. 319 377 8263 www.freund-vector.com

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