HD Insights™

Vol. 9 - Winter 2014

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H D I N S I G H T S T M T H A N K S L U N D B E C K F O R I T S G E N E R O U S S U P P O R T Copyright © Huntington Study Group 2014. All rights reserved. SPONSOR STUDY NAME/ IDENTIFIER STUDY AGENT PHASE PRINCIPAL INVESTIGATOR, CONTACT DESIGN TRIAL LENGTH SITES STATUS Teva Pharmaceutical Industries PRIDE-HD Pridopidine II Teva US Medical Information 800-896-5855 Randomized, double-blind, placebo-controlled study of safety and efficacy of pridopidine 45 mg, 67.5 mg, 90 mg, and 112.5 mg BID versus placebo for symptomatic treatment in patients with HD 26 weeks U.S. Currently enrolling Teva Pharmaceutical Industries OPEN-HART Pridopidine II Karl Kieburtz, MD, MPH Open-label, single group assignment study to assess the long-term safety of 45 mg of pridopidine in HD participants 2 years 22 sites - U.S. and Canada Enrollment complete, study ongoing Teva Pharmaceutical Industries Legato-HD Laquinimod II Teva US Medical Information 800-896-5855 Randomized, double-blind, placebo-controlled, parallel-group study evaluating efficacy and safety of Laquinimod (0.5, 1.0 and 1.5 mg/day) in HD 12 months 46 sites - worldwide Not yet recruiting Clinical Trials, cont... To update or add a clinical trial, please e-mail editor@hdinsights.org. Sources: www.clinicaltrials.gov and apps.who.int/trialsearch/ H D I N S I G H T S HD Insights, Vol. 9 11

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