Issue link: https://www.e-digitaleditions.com/i/1022930
12 September 2018 Tablets & Capsules N early every company that manufactures tablets has had to deal with a sticking problem during compression. Despite the problem's ubiquitous nature, cross-functional collaborations to discuss sticking across the pharmaceuti- cal industry have either been very limited or absent alto- gether. To address this gap and facilitate precompetitive dialogue on this important topic, in 2016 the International Consortium for Innovation and Quality in Pharmaceutical Development (IQ Consortium) formed a Sticking during tablet compression is a problem that the phar- maceutical industry has faced since the advent of the dosage form more than 100 years ago, yet it is still a relatively poorly understood phenomenon. This article presents the results of a survey of IQ Consortium member companies that focused on the prevalence of sticking, the state of predictive tools and mod- els, and experiential solutions to mitigate the problem. Industry perspectives on sticking during tablet compression Sayantan Chattoraj, Patrick Daugherity, Todd McDermott, Angela Olsofsky, Wyatt J. Roth, and Mike Tobyn IQ Consortium tableting Courtesy of Natoli Engineering