Issue link: https://www.e-digitaleditions.com/i/1087673
Tablets & Capsules March 2019 31 Selecting a WIP or CIP deduster While WIP and CIP dedusters cost more than dust- tight and non-dust-tight dedusters, the added cost of either type typically represents only a small part of the cost of a containment press and suite. However, because the deduster removes hazardous dust from tablets, the choice is important. The deduster is part of a contained system in which the tablet press, deduster, and contained tablet collection container must work together seamlessly. Because you can opt for functional and operational customizations to fit your production and user needs, you should develop a user requirements specification (URS) to document all system expectations and obtain approval from all user groups. Answer the following questions prior to purchasing a WIP or CIP deduster: • What are our normal production requirements? • How hazardous is our product? What operator exposure limit (OEL) level—operator exposure limit times the weighted average—do the materials being handled require? • How easy is a particular deduster to assemble and disassemble? • What layout do we require to handle upstream and downstream processes? • How will we control water flow, and do restrictions on water usage exist? Dust-tight tablet dedusters have positive connections to upstream and downstream equipment along with gas- kets and seals to prevent dust migration during opera- tion, but like non-dust-tight dedusters, they also require disassembly for cleaning and are unsuitable for hazard- ous or highly potent formulations. To protect operators and washing personnel in hazardous applications, you must use either a wash-in-place (WIP) or clean-in-place (CIP) deduster. WIP dedusters are dust and water tight and meet vali- dated containment levels during operation. WIP machines allow the introduction of water, or water and detergents, into the machine, with all areas becoming fully wetted without disassembly. The water washes the machine's entire inside, preventing dry-powder exposure and removing most powder from the machine. This allows the operator or cleaning personnel to safely disas- semble the machine for final manual cleaning and drying, with no dust hazard. Like WIP dedusters, CIP machines are dust and water tight and meet validated containment levels during operation, but they also use validated cleaning protocols to verify that no residual material remains in the machine. You can fully clean and dry CIP machines without disassembly. They require no human interven- tion, allowing you to run another product or batch as soon as the CIP machine has completed the washing and drying cycle. World-Leading Trade Fair for Processing, Analysis, and Handling of Powder and Bulk Solids Honorary sponsors Together with First comes the experience, then the success: discover the entire spectrum and dynamic energy of mechanical process engineering. POWTECH is the trade fair event for bulk solids – and the place where process optimisation begins. Professional knowledge right from the experts and contacts that will help you move ahead: The supporting programme will make your trade fair visit even more worthwhile with the following highlights: • Expert Forums for Chemistry and Food • Pharma.Manufacturing.Excellence. Forum • Networking Campus • Special display area for explosion protection • VDMA Special Show: Dust knows no borders EXPERIENCE THE DYNAMIC ENERGY, SHARE KNOWLEDGE, OPTIMISE PROCESSES APRIL 9-11, 2019 NURNBERG, GERMANY