Tablets & Capsules

TC1019

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Tablets & Capsules October 2019 35 Figure 2 PCA model (score plot) for 300+ batches of SuperTab 30GR taken over a 7-year period Hotelling's T 2 95% confidence limit t[2] 4 3 2 1 0 -1 -2 -3 -4 -5 t[1] -4 -3 -2 -1 0 1 2 3 4 2011 2012 2013 2014 2015 2016 2017 R 2 x[1] = 0.158 R 2 x[2] = 0.14 Figure 3 Loading plot for 300+ batches of SuperTab 30GR taken over a 7-year period Density Impurity Moisture Particle size Specification p[2] p[1] 0.6 0.5 0.4 0.3 0.2 0.1 0 -0.1 -0.2 -0.3 -0.4 -0.3 -0.2 -0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 R 2 x[1] = 0.158 R 2 x[2] = 0.14 PSD %<355 micron PSD %<150 micron Sulphated ash (%w/w) KF (%w/w) Acidity Calculated dry matter Specific rot. (o) LOD (%w/w) Hausner ratio Color, 400nm UV 210-220nm UV 270-300nm Bulk density (kg/m 3 ) Tapped density (kg/m 3 ) PSD %<75 micron

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