Tablets & Capsules

TC1019

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Tablets & Capsules October 2019 39 9. G. Thoorens, et al., "Understanding the impact of microcrystalline cellulose physicochemical properties on tabletability," International Journal of Pharmaceutics, 2015, Vol. 490, No. 1, pages 47-54. 10. A. P. Ferreira, et al., "Multivariate analysis in the pharmaceutical industry: enabling process understanding and improvement in the PAT and QbD era," Pharmaceuti- cal Development and Technology, 2015, Vol. 20, No. 5, pages 513-527. 11. M. Tobyn, " Back page: Excipient variabilit y: Mostly a fuss," Tablets & Capsules, September 2015. 12. G. A. Hebbing and B. H. J. Dickhoff, "Application of lactose in the pharmaceutical industry," Chapter 5 in Lactose—Evolutionary role, health effects, and applications, Aca- demic Press, 2019, pages 175-229. 13. J. M. Newton, et al., "The strength of tablets of mixed components," Journal of Pharmacy and Pharmacology, 1977, Vol. 29, No. 1, pages 247-249. 14. A. S. El Hagrasy, et al., "Twin screw wet granu- lation: Influence of formulation parameters on granule properties and growth behavior," Powder Technology, 2013, Vol. 238, pages 108-115. 15. V. Moolchandani, et al., "Characterization and selection of suitable grades of lactose as functional fillers for capsule filling: part 1," Drug Development and Industrial Pharmacy, 2015, Vol. 41, No. 9, pages 1,452-1,463. 16. H. Listiohadi, et al., "Moisture sorption, compress- ibility and caking of lactose polymorphs," International Journal of Pharmaceutics, 2008, Vol. 359, No. 1-2, pages 123-134. 17. A. Combas, et al., "Quantitative determination of crystallinity of α-lactose monohydrate by DSC," Journal of Thermal Analysis and Calorimetry, 2002, Vol. 68, No. 2, pages 503-510. 18. E. Berlin, "Calorimetric measurement of the heat of desorption of water vapor from amorphous and crys- talline lactose," Thermochimica Acta, 1971, Vol. 2, No. 2, pages 143-152. 19. M. D. Ticehurst, et al., "Characterisation of the surface properties of α-lactose monohydrate with inverse gas chromatography, used to detect batch variation," International Journal of Pharmaceutics, 1996, Vol. 141, No. 1-2, pages 93-99. B. H. J. Dickhoff is development manager, oral solid dose; T. Schigt is research specialist; H. L. Blaauw is category man- ager, marketing; and A. W. van Gessel is regional sales and marketing manager, Japan, at DFE Pharma (+492823 9288 770, www.dfepharma.com).

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