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A technical article discusses using synchrotron radiation to gain new insights into pMDI design. The first in an article series on limitations of metrics commonly used in the assessment of APSDs for OIPs discusses the surprisingly limited utility of the fine particle dose metric in quality control. The cross-industry organizations column provides an update about ISAM and Back Page discusses a study of poplar trees genetically modified not to damage air quality that gives reasons for optimism about environmental sustainability and fossil fuel alternatives. 2 April 2020 Inhalation Inhalation (ISSN 1937-0717 print; ISSN 1940-414X online) is published six times per year in February, April, June, August, October and December by CSC Publishing, Inc., 1155 Northland Drive, Saint Paul, MN 55120. w w w . i n h a l a t i o n m a g . c o m April 2020 Volume 14 Number 2 Cover photo shows the Xelair ® 5 automated delivered dose unifor- mity system with 6-axis robot and dry powder inhaler storage. From Astech Projects, Ltd., 15 Berkeley Court, Manor Park, Runcorn, Cheshire, WA7 1TQ, United Kingdom, Tel.: +44 1928 571797, Inhalation instruments 10 Gaining new insights into pressurized metered dose inhaler (pMDI) design using synchrotron radiation Daniel J. Duke 23 Issue focus: Instruments education 25 Special section: Education additional features 6 Cross-industry organizations: ISAM: 2019 highlights and a preview of 2020 activities Philip J. Kuehl, Andrew Martin and Chantal Darquenne 18 The liability of fine particle dose (FPD) Adrian P. Goodey, Jolyon P. Mitchell, William H. Doub and J. David Christopher 27 Extra focus: Product development 32 Back Page: Poplar trees genetically modified not to damage air quality grow as well as non-modified trees departments 8 Industry news 30 Calendar Cover 3 Web review

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