Inhalation

INH0422

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Inhalation April 2022 35 Dual cavity multi-dose DPI e MRX006 is a dual cavity, multi-dose dry powder inhaler (DPI) device. It offers superior technology, tailored to current regulations and high-performance expectations. Based on the open-inhale-close prin- ciple, it is designed to accommodate a combination formulation of two or more active pharmaceutical ingredients (APIs) to enable filling of the generic DPI, for instance with fluticasone, umeclidinium and vilanterol. Merxin UK: +44 1553 406070 info@merxin.com www.merxin.com Dry powder inhalation capsule portfolio Lonza's Capsugel ® Zephyr™ dry powder inhalation capsule portfolio is a comprehensive capsule prod- uct offering, featuring customized DPI capsules and dedicated equipment in place for efficient, phase- appropriate capsule filling. e Zephyr DPI portfolio addresses the need for highly customized solutions for pulmonary route delivery methods and is supported by Lonza's inhalation and drug development and par- ticle engineering capabilities. is integrated product and service offering enables consistent and optimal release performance for inhalation drugs. Lonza Capsules & Health Ingredients US: +1 888 783-6361 www.capsugel.com Capsules for pulmonary drug delivery technologies Dry powder inhalers (DPIs) come in many forms: single-dose devices with the drug either pre-dispensed into capsules and blisters or multi-dose devices with a bulk drug reservoir and a measuring instrument. With extensive expertise in this field, Qualicaps ® offers a broad portfolio of capsules in gelatin and HPMC especially designed for inhaled drug delivery, with superior aerosolization and puncturing proper- ties, even for very hygroscopic and very moisture-sen- sitive inhalation formulations. Qualicaps ® Europe, S.A.U. Spain: +34 91 6 63 0 800 www.qualicaps.com

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