SOLID DOSAGE
4 Manufacturing OSD Forms:
Key Trends Shaping the Industry
Laxman Shetty, Jnanadeva Bhat, and Anita Solanki
10 Don't Gamble on Tablet Tooling Maintenance
Andy Dumelow
BIOLOGICS
16 Opportunities for Growth
and Breakthroughs for Cell and Gene Therapies
Meg Rivers
22 Plan Early: Optimizing
Stability During Lyophilization
Feliza Mirasol
CONTINUOUS MANUFACTURING
30 Demonstrating a Fully Continuous Bioprocess
Jennifer Markarian
36 Implementing Continuous
Bioprocessing: From Theory to Practice
Feliza Mirasol
ASEPTIC PROCESSING
40 Using Robotics in the Aseptic
Manufacturing Facility of the Future
Richard Denk, Julien Janda, Markus Stuebchen, and David Wolton
COMBINATION PRODUCTS
52 Converting Injectable Therapies to
Combination Drug-Device Products
Markus Hörburger
OPERATIONS
58 Embracing New Realities
Grant Playter
60 The Lighthouse Effect: Using Technology
to Improve Life Sciences Manufacturing
Gul Dusi
62 Ad Index
Cover image: zapp2photo, Paulista - stock.adobe.com; Cover design, Maria Xelo
Trends in Manufacturing 2022
EDITORIAL
Editorial Director Chris Spivey CSpivey@mjhlifesciences.com
Senior Editor Felicity Thomas FThomas@mjhlifesciences.com
Senior Editor Meg Rivers MRivers@mjhlifesciences.com
Managing Editor Susan Haigney SHaigney@mjhlifesciences.com
Science Editor Feliza Mirasol FMirasol@mjhlifesciences.com
Assistant Editor Grant Playter GPlayter@mjhlifesciences.com
Assistant Editor Alivia Leon ALeon@mjhlifesciences.com
Creative Director, Publishing Melissa Feinen
Senior Art Director Marie Maresco; Senior Graphic Designer Maria Xelo
Contributing Editors Jill Wechsler jillwechsler7@gmail.com;
Hallie Forcinio editorhal@cs.com; Susan J. Schniepp sue.schniepp@mac.com;
Cynthia A. Challener, PhD challener@vtlink.net, and Jennifer Markarian
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SALES
Publisher Mike Tracey MTracey@mjhlifesciences.com
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Audience Development
Stacy Argondizzo SArgondizzo@mjhlifesciences.com
MJH LIFE SCIENCES®
President & CEO Mike Hennessy Jr
Chief Financial Of ficer Neil Glasser, CPA/CFE
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Vice President, Mergers & Acquisitions Chris Hennessy
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