Issue link: https://www.e-digitaleditions.com/i/1468049
48 Pharmaceutical Technology TRENDS IN MANUFACTURING 2022 eBOOK P h a r mTe c h . c o m Aseptic Processing in aseptic manufacturing. Examples relevant to robotics are artificial intelligence (AI), Internet of Things sensors, 5G, and cloud technology, to name a few. The relevance of these technologies to robotics is that the more those technologies mature, the more the implementation of robotics will benefit and accelerate. Hence, it is essential to keep track of their development and how the organization and industry apply them to robotics and other applications. To summarize, as illustrated in Figure 3, the more one combines crucial IT and OT interfaces, a rethinking and redesigning of manufacturing operations at the core of pharmaceuticals, and convergent technologies while taking the enablers into account, the more mature the Facility of the Future will become. A vision for the future To accelerate change, a common vision is needed to focus both end users and suppliers. With this in mind, a roadmap was developed by the BioPhorum Operations Group (BPOG) (2). The milestones of Version 1 of this roadmap, shown in Figure 4, can be summarized as follows: • Milestone 1: Mapping of a packaging facility from goods in, to goods out. Mundane tasks (e.g., removing shrink wrap from pallets, ap- plying bar codes, opening boxes, collapsing boxes for recycling) are either removed or au- tomated. The first step on this journey is to create a value stream map in order to step back and look at the whole packaging facility from a lean perspective. • Milestone 2: Using robots to pass materials © BioPhorum Operations Group Ltd v2 2020 1 Robotics technology biomanufacturing roadmap to 2030 (v1. Mar 2022) Lights-out packaging Start of mapping goods-in to goods- out for secondary packaging Q1 2023 1 Lights-out material transport Start of testing of automated material Air Lock Prototype Q3 2023 2 Goods-in automation Key consumables suppliers engaged in prototyping automated goods-in systems Q3 2024 4 5 Lights-out secondary packaging facility Total automation from goods-in to goods-out Q4 2027 6 Lights-out cell therapy facility Total automation from goods-in to goods-out Q3 2029 8 Lights-out inoculum laboratory Total automation of the inoculum lab Q1 2028 7 Mobile sampling Taking of samples by mobile robots 24/7 Q2 2024 3 1 4 2 3 4 5 7 1 BioPhorum will identify use cases for prioritization Prototype QC lab QC analytical equipment adapted for operation by plug & play mobile robots Q1 2026 2022 2024 2026 2028 2030 Figure 4. A roadmap (version 1) presents a common vision for the facility of the future. Figure is courtesy of BioPhorum. FIGURE IS COURTESY OF BPOG