Inhalation February 2023 23
Particle engineering
Particle engineering is being used increasingly in
drug development, particularly for complex dosage
forms such as OINDPs, where controlled deposition
in the respiratory system is key to efficacy. Particle
engineering offers multiple options for tailoring the
particle size to optimize and target delivery to a spe-
cific region, as well as offering a controlled manufac-
turing process to build a stable, engineered product
that has significant advantages for the formulation of
biologics. Intertek has recently invested in spray dry-
ing to further our capabilities in the development of
respiratory products.
Intertek Pharmaceutical Services
UK: +44 1763 261648
bd.melbourn@intertek.com
www.intertek.com
Multidose soft mist inhaler
Merxin's MRX004 is a multidose soft mist inhaler
for deep lung deposition and easy use, designed for
aqueous and ethanol formulations, including biolog-
ics. e MRX004 can be used with any molecule that
would benefit from lung delivery, for local action or
systemic delivery, or re-purposing existing molecules
away from nebulizers, dry powder inhalers (DPIs)
or pressurized metered dose inhalers (pMDIs) into a
much more efficient and greener device. It also can
be ideal for those products that would benefit from a
reduced dose.
Merxin
UK: +44 1553 406070
info@merxin.com
www.merxin.com
Metered dose inhaler
(MDI) re-formulation
Momentum towards re-formulating metered dose
inhalers (MDIs) with a "greener" propellant contin-
ues to grow. Demand for MDIs remains high, add-
ing impetus to requirements for testing solutions that
expedite re-formulation timelines. Compatible with
most MDI device types and a wide range of dose
collection devices, the Vertus
®
automated shake and
fire range offers total test method control to improve
data integrity and reproducibility, reducing the risk of
costly re-formulation testing delays. Accelerate your
MDI testing: bit.ly/Vertus-Shake-Fire-Flow.
Copley Scientific
UK: +44 1159 616229
sales@copleyscientific.co.uk
www.copleyscientific.com
