Inhalation

INH0224

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22 February 2024 Inhalation Bespoke inhaled formulation development i2c Pharmaceutical Services is a leading independent service provider to global pharma, medical technol- ogy and emerging companies for the development of inhaled formulations and efficient devices. i2c provides bespoke integrated services from ab initio development through clinical trials. i2c also offers Respitab ® ; this propellant-dispersible tablet is a cost-effective and innovative manufacturing platform that can facilitate transition to the next generation of pressurized metered dose inhalers (pMDIs). i2c Pharmaceutical Services UK: +44 2920 757865 www.i2cpharm.co.uk DPI development and manufacturing services Experic's experienced team provides customized spray drying, precision filling, analytical support and pack- aging solutions at clinical and commercial scale for reservoir and single-dose dry powder inhalation (DPI) products. From formulation development and GMP manufacturing in low humidity environments to clin- ical trial supplies and global logistics, Experic offers services that can solve development and manufactur- ing challenges, accelerate time to market, and mitigate risk for inhalation products with a range of properties. Experic, LLC US: +1 609 537-4040 www.expericservices.com Nasal formulation development and manufacturing Renaissance Lakewood offers contract development and manufacturing for nasal sprays. We can support all stages of projects, from formulation development through commercial manufacturing. With over 20 years of experience, our team can support a wide range of development activities including formulation development/optimization, spray method develop- ment, device selection, clinical trial material, process development and stability studies. In addition, we can support a wide range of nasal spray devices, includ- ing unit-dose, bi-dose and multi-dose (preserved and non-preserved formulations). Renaissance Lakewood US: +1 732 367-9000 www.renpharm.com Dry powder inhalation capsule portfolio Lonza's Capsugel ® Zephyr™ dry powder inhalation (DPI) capsule portfolio is a comprehensive capsule product offering, featuring customized DPI capsules and dedicated equipment in place for efficient, phase- appropriate capsule filling. e Zephyr DPI portfolio addresses the need for highly customized solutions for pulmonary route delivery methods and is supported by Lonza's inhalation and drug development and par- ticle engineering capabilities. is integrated product and service offering can enable consistent and optimal release performance for inhalation drugs. Lonza Capsules & Health Ingredients US: +1 888 783-6361 www.capsugel.com

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