Inhalation

INH0224

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Inhalation February 2024 29 ticle Formation of Leucine in Spray Drying of Inhalable Microparticles. International Journal of Pharmaceutics 2021, 592, 120102, doi:10.1016/j. ijpharm.2020.120102. 22. Ordoubadi, M., Shepard, K.B., Wang, H., Wang, Z., Pluntze, A.M., Churchman, J.P., Vehring, R. On the Physical Stability of Leucine-Containing Spray-Dried Powders for Respiratory Drug Deliv- ery. Pharmaceutics 2023, 15, 435, doi:10.3390/ pharmaceutics15020435. Mani Ordoubadi, PhD, is a postdoctoral fellow at the University of Alberta, Edmonton, Alberta, Canada, ordoubad@ualberta.ca. 12. Lucassen-Reynders, E.H., Cagna, A., Lucas- sen, J. Gibbs Elasticity, Surface Dilational Modulus and Diffusional Relaxation in Nonionic Surfactant Monolayers. Colloids and Surfaces A: Physicochem- ical and Engineering Aspects 2001, 186, 63-72, doi:10.1016/S0927-7757(01)00483-6. 13. Miller, R., Fainerman, V.B., Pradines, V., Koval- chuk, V.I., Kovalchuk, N.M., Aksenenko, E.V., Lig- gieri, L., Ravera, F., Loglio, G., Sharipova, A., et al. Surfactant Adsorption Layers at Liquid Interfaces. In Surfactant Science and Technology; CRC Press, 2014; pp. 149-169. 14. Eastoe, J., Dalton, J.S. Dynamic Surface Ten- sion and Adsorption Mechanisms of Surfactants at the Air–Water Interface. Advances in Colloid and Interface Science 2000, 85, 103-144, doi:10.1016/ S0001-8686(99)00017-2. 15. Gliński, J., Chavepeyer, G., Platten, J.-K. Surface Properties of Aqueous Solutions of L-Leucine. Bio- physical Chemistry 2000, 84, 99-103, doi:10.1016/ S0301-4622(99)00150-7. 16. He, Y., Yazhgur, P., Salonen, A., Langevin, D. Adsorption–Desorption Kinetics of Surfactants at Liquid Surfaces. Advances in Colloid and Inter- face Science 2015, 222, 377-384, doi:10.1016/j. cis.2014.09.002. 17. Gomez, M., McCollum, J., Wang, H., Ordou- badi, M., Jar, C., Carrigy, N.B., Barona, D., Tetreau, I., Archer, M., Gerhardt, A., et al. Development of a Formulation Platform for a Spray-Dried, Inhal- able Tuberculosis Vaccine Candidate. International Journal of Pharmaceutics 2021, 593, 120-121, doi:10.1016/j.ijpharm.2020.120121. 18. Carrigy, N.B., Liang, L., Wang, H., Kariuki, S., Nagel, T.E., Connerton, I.F., Vehring, R. Trileucine and Pullulan Improve Anti-Campylobacter Bacterio- phage Stability in Engineered Spray-Dried Micro- particles. Annals of Biomedical Engineering 2019, doi:10.1007/s10439-019-02435-6. 19. Wang, Z., Wang, H., Vehring, R. Leucine Enhances the Dispersibility of Trehalose-Containing Spray-Dried Powders on Exposure to a High-Hu- midity Environment. International Journal of Pharmaceutics 2021, 601, 120561, doi:10.1016/j. ijpharm.2021.120561. 20. Mah, P.T., O'Connell, P., Focaroli, S., Lundy, R., O'Mahony, T.F., Hastedt, J.E., Gitlin, I., Oscarson, S., Fahy, J.V., Healy, A.M. e Use of Hydropho- bic Amino Acids in Protecting Spray Dried Trehalose Formulations Against Moisture-Induced Changes. European Journal of Pharmaceutics and Biophar- maceutics 2019, 144, 139-153, doi:10.1016/j. ejpb.2019.09.014. 21. Ordoubadi, M., Gregson, F.K.A., Wang, H., Nicholas, M., Gracin, S., Lechuga-Ballesteros, D., Reid, J.P., Finlay, W.H., Vehring, R. On the Par-

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