Issue link: https://www.e-digitaleditions.com/i/1524818
A technical article outlines the factors that could influence in vitro dissolution of pMDI aerosols, offering guidance for optimizing formulation design by selecting appropriate APIs and excipients, as well as enhancing the manufacturing process. A point of view article about switching propellants for metered dose inhalers (MDIs) in the 1990’s vs. 2020’s provides commentary, perspective and recommendations. 2 August 2024 Inhalation Inhalation (ISSN 1940-414X digital) is published seven times per year in January, February, April, June, August, October and December by Whipsnade and Loophole, LLC, P.O. Box 27092, Minneapolis, MN 55427 US. w w w . i n h a l a t i o n m a g . c o m August 2024 Volume 18 Number 4 The cover photo shows a Next Generation Impactor, used to test inhalers. Photo courtesy of Catalent Inhalation, 190 Everett Avenue, Chelsea, MA, 02150, US, www.catalent.com/inhalation particle characterization 10 Factors influencing the in vitro dissolution rates of pMDI aerosols Lin Zhang, William Glover, David A. Lewis, Robert D. Johnson, Daniel I. Lewis, Paul M. Young, and Hui Xin Ong 19 Issue focus: Particle characterization particle manufacturing 31 Special section: Particle manufacturing additional features 6 Cross-industry organizations: ISAM: 2023 highlights and a preview of 2024 activities David Cipolla and Barbara Rothen-Rutishauser 22 Point of view: MDI propellant switching in the 2020's vs. 1990's: Commentary, perspective and recommendations Richard (Rik) Lostritto 35 Back page: Student volunteer organization coordinates donations of 100,000+ allergy-friendly food items to pantries departments 8 Industry news 33 Respiratory medicine news 33 Calendar 34 Literature review