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www.gamlen.co.uk USING THE GAMLEN ® TABLET PRESS GTP-1 COMPARING TABLETS USING TENSILE FRACTURE STRESS, COMPACTION FORCE AND DENSITY Tensile Fracture Stress (MPa) Compaction Pressure (MPa) Tabletability, compactibility and compressibility Solid Fraction Tensile Strength (MPa) Compaction Pressure (MPa) Tensile Strength (MPa) Compaction Pressure (MPa) Solid Fraction Tabletability Compactibility Compressibility G N I S U M A GA E TH G N LE M ® L B A TA S G S E T PR E L 1 - P T S G G N I S U C n ( o t w e d N n l a l e F w t o s h a t w s r e fi Th a l ta a c i r d n i l y f a c o b a n t s i e c n e r e f f i d M A GA E TH G E L B A TA G RIN A PA M O C C AC PA M O C t d n a t r o p m o i w e t d * ma ) 8 6 9 1 n ( e s r u t c a r e f l i s n e e t e th t la u c l a o c w t e ke a d ta n , a ) la u m r o e fo se t ( e l b a r t e t me a i d d n s a s e n k c i t th e l b N LE M L B A TA E IL S EN T G N I S U S T E D D N E A C OR ON F I T . s e i r e v o sc i t d s s e tr e s ı t ) FS T ( t n ou c c o a to n e i n t a i m r e o p r t ) a 2 1.8 1.6 S G S E T PR E L , S S RE T S RE U T C AC R F Y T I S N E D D 1 - P T S G l e c vi A a tr x E se o t c La e l g g e M b a n t s i e c n e r e f f i d so i r a p m o c e t a r u c c a h s n o i t la e e r t th a th r a e n i l s i S TF d n a y t i l i ab t e l ab t " d e l l a c ı t = 2P ʌDt c r t e t me a i d d n s a s e n k c i t th e l b e Th . s e i t r e p o r p t e l b a t f n o so t c a p m o t c e l b a n t e e w t e p b i h q bse u s s a h r e t me a r a p s i Th . r . " y * 1 0 ( l 2 o c a m r a h m P r a h . J P n J M o t w e d N n l J T a l e F o c t e l b a e r e a w S TF g n i s U y a l k c i u s q t e l b a f t s o e i t r e p o r p e t f ma s o t n ou m l a l ma g s n i s u s u t e l b a w t e e a f r u t c a f u n ma a e ol f tr n o e c c r o n f o i t c a p m o c n t a i m r e o p r t s a w d n o c se e r u s s e r n p o i t n e e b y tl n e u q 8 5 7 - 6 5 ) 6 8 6 9 e th e r a p m o o c , y l i s a d e n y a y l p m i . S l a i r e e g th n i s s u - TP f G e o r u t a MP ( s s tre S re u t c a r F e l i s n e T 1.4 1.2 1 0.8 0.6 0.4 0.2 se o t c La V M D d e t a l u n ra G et W se o t c La C D e t a r d y oh on M e s o t c a L 0 0 5 h 1 c r a t S ® t es Te s es n d r a H th c d t bili a ta e l b a Ta r p m o c nd a l b ty ty ty p e t f th S o e TF e th r u s a , me 1 a o e l l b a t i u th a s i 1 w - TP e G th r e t s e t s s ne d r ha l ona i t n e v on c r e t n ma e e w t e s b e c n e r e f f i d . t n e r a p p s a me o c e b y t bili i t c a p m o c , y, t y t bili i s s e r la t f l b d t g n i s u t ( e l b a e t r a , o l l e d c a he t nd a , ) r y l k c i u s q l a i r 0 40 e l p m a x n e s a A n th n o o i t la u n a ra g . Th l 3.50 3.00 2.50 ) a MP ( th te t Fe -1 P T G ) a P M ( e r u s s e r P on i t c ompa C 60 80 0 10 0 12 y o d u t d a s e h s i l b u y p tl n e c e e r , w e o t c ola n o ro i p f s y o t i l i b a t e l b a e t n th y t bili a t e l b a Ta 0 14 f t o c e fe f e e n th y o … s n o i t la u m r o e fo n o s a t e l b a g t n i r a p m o C ou ma n y e se wh u a c e b e a s th . A me i me t sa , th s se a e re c e t d e l b a t m i e l b o r r p e th r u A f l w a n i m o me n e sa th f f i s d l a i r e t t ma s o m s b p i h s n o i t la e r e Th or y t i s n e d ( on i t ac fr u g i n F d i se i r ma m u s y i t i l i b t l b T t s o s n s i n o i t la u m r o t fo e l b a d t n s a e t me a ra a l p a r e v , se t e l b a e a t ke ou ma i e th , th s se a e re c n e i c rc o d fo e i l p p e a s n e e d d th n , a s e c u d e y re t i s o ro o e p p m o o c r t e th e e wh d i c e o d s t m i a n i m o me n e sa r th t o h g i e l w f i e d v i l g l i s w i , th y t i s n e n d r i e f tr s e r u t c a r e f l i s n e n t e e w t e s b on i t ac p om c nd a ) y t i os or p or . e 1 r u h i t la s th d a efi s d s s i i . Th e l p m i t s e t th y a r a s v r e e f th s o s e n k c . s se a e re c n y i t i s f s o t e l b a e t r a s ; a me u ol l v . s t l u s e t r n e r e f f d i sol , th g n e tr e r a e r u s s e r p t p b i 2.00 1.50 1.00 0.50 0.00 0 70 0. th g n tre S e l i s n e Te 1.00 0.95 0.90 0.85 on i t te t Fe -1 P T G 75 . 0 .80 0 .85 0 .90 0 on i t c a r F d i ol S te -1 y t bili i s s e r p m o C .90 5 .95 0 .00 1 s d y i t i l i b a t e l b a Ta u s s e r p on i t ac p om c i sol s se r e v e re u s s e re p d sol n S a n TF e e w t e b s s t o l p e . Th l a i r e t ma d TF n n a o i t c a ra d f i sol Y TY TY IT ILI BI p m o C s re P h s n o i t la e e r s th d a e n efi s d s i y t i l i b i s s e re p om C . S F T nd a e re u th s i y t i l i b i t c a p m o C . n o i t c a r f d i d t e d e e e n r l a l . A n o i t c a r d f i d sol n o i t c a p m o f c o t c e fe f e e th w o h s s ) f K S G e ( n i l K th i m oS x la f a G S o d TF n o i t ac p re u s s L T BL AB TA n e e w t e p b i on i t ac p om c s p i h s n o i t la e re e e a n efi o d d t n e o re u s s e re p n . n o i t la u m r o fo 4.5 4 3.5 ) a MP 0.85 0.80 0.75 0.70 0.65 0.60 0.00 t c a r F d i ol S te t Fe -1 P T G 50.00 00.00 1 50.00 1 200.00 ) a P M ( e r u s s e r P on i t c ompa C te -1 y t bili i t c a p m o C 200.00 250.00 00 . 00 3 IB C SI SS RES PR MP OM CO CO A C PA OM C id ol S n o i t ac r F w 1 e r u g Fi Y IT L I B I T C AC e l si n e Te th ng e tr S Y TY LI LIT BI BIL AB LETA BL k u o. c . n e l m a .g w. w w 3 2.5 2 1.5 1 0.5 0 0 MP ( th g n tre S e l i s n e Te k ) a P M ( e r u s s e r P on i t c ompa C 50 0 10 0 15 200 250 300 Sourcebook_PBE-CCR 6/10/14 1:29 PM Page 31

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