Issue link: https://www.e-digitaleditions.com/i/341135
18 July 2014 Tablets & Capsules Silicified microcrystalline cellulose Prosolv silicified microcrystalline cellu- lose imparts excellent flow, compaction, and matrix dispersion to tablet formula- tions. It can replace granulation steps when used in direct compression for- mulations and reduce quantity of excip- ients required. High-functionality excipient requires less complex process- ing, improves compaction and produc- tion capacity, and can speed formula- tion development. JRS Pharma, Patterson, NY. Tel. 845 878 3414 Fax 845 878 3484 www.jrspharma.com Tricalcium phosphate-guar gum combination Nutra Tab granulated tricalcium phos- phate with guar gum—specifically designed for nutraceutical formula- tions—improves compressibility of direct-to-press formulations, maintain- ing good flow and disintegration while boosting calcium and phosphorus con- tent. Co-processed excipients' natural guar gum coating provides pleasant mouth-feel to chewable tablets by masking chalkiness and grittiness asso- ciated with calcium excipients. Com- pany also supplies A-Tab, Di-Tab, and Tri-Tab di- and tricalcium phosphates. Innophos, Cranberry, NJ. Tel. 609 495 2495 Fax 609 860 0138 www.innophos.com Ultrafine HPC HPC-SSL Superfine Powder (SFP) hydroxypropyl cellulose is ultrafine, super-low- viscosity grade that promotes high compressibility in dry-binding applications. Low viscosity (2 to 2.9 millipascal-seconds @ 20°C and 2 percent aq) allows rapid disin- tegration and dissolution compared to other grades of HPC, while its fine (20- micron) particles allow low use levels to achieve desired tablet properties for which HPC is well known. Compared to common dry binders, excipient produces harder tablets and lower friability without hindering API release. HPC can be used with direct-compression immediate-release tablets, orally disintegrating tablets, roller- compacted/dry granulations, HPMC matrix tablets (hardness enhancement), and poorly compressible APIs. It can also assist binding of high-API-loaded tablets, reduce tablet size, and minimize capping. Nisso America, New York, NY. Tel. 212 490 0350 Fax 212 972 9361 www.nissoexcipients.com d-FOCUS_16-21_Masters 7/2/14 11:07 AM Page 18