Tablets & Capsules

TC0115A

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Tablets & Capsules January 2015 35 A survey of what's available Bathless disintegrator SensIR 3200 bathless disintegrator eliminates mess and inconvenience of conventional water-bath instruments. Unit comes with two, four, or six disintegration stations within small footprint; it heats media from room temperature to 37°C in less than 8 minutes. NIR provides endpoint detection without need for modified fluted disk. Disintegration baskets operate independently or in unison, increasing throughput. Basket mounting mechanism eliminates undesirable sway. Unit is controlled by touch-screen interface and meets or exceeds all harmonized compendial requirements. It stores as many as 100 reports and methods. Distek, North Brunswick, NJ. Tel. 732 422 7585 www.distekinc.com Dissolution testing webinar Recording of June 2014 webinar, "Method Development, Including Design of Experiments (DoE) in Dissolution Testing," examines how to develop effective dissolution tests using QbD principles. Topics include assessing how dosage form's excipients, stability performance, BCS rating, and other properties affect test development; causes and cures of variability; f2 rules and when to apply them; how to justify using sodium lauryl sulfate and surfactants; selecting apparatuses; how to obtain specifications relevant to CQAs; how to account for property and process variables in DoEs; setting clinically relevant specifications; establishing in vitro- in vivo relationship; and complying with ICH 6A. Presenter is Vivian Gray, who also addressed "Dissolution Testing: New Performance Acceptance Criteria for Calibrator Tablets and Sources of Error" in a March 2012 webinar. Catalog of all solid dosage webinars is available at T&C's online bookstore. Tablets & Capsules, St. Paul, MN. Tel. 651 287 5600 www.tabletscapsules.com dissolution testing Modular dissolution testing equipment Xtend dissolution line's modular components offer flexibility in R&D and QC labs and ease scale-up. Dissolution bath, pump, filter station, and sample manager combine as needed to meet automation requirements, from manual to semi- and fully automated operation. System can include AT circular dissolution bath apparatus that performs USP 1, 2, 5, and 6 test methods. Touch-screen control (photo) with icon-based menu and multiple-language capability simplifies setup, method programming, and data management. AT MD configuration runs as many as 8 unattended tests in succession using fully automated media preparation, gravimetric dispensing to vessels, and between-lot flushing. AT 70smart configuration allows batching of up to 15 unattended tests. Durable components allow round-the-clock operation. Sotax, Westborough, MA. Tel. 508 417 1112 www.sotax.com

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