Issue link: https://www.e-digitaleditions.com/i/648486
Tablets & Capsules March 2016 15 piece of equipment figures out how to do the operation," Jayjock said. "It means when clients come to us with a product they've developed, we can help transfer it in. If for some reason it must be transferred out, that'll be a big advantage for them. Even internally, it will enable us to transfer between dif- ferent sites with a high chance of suc- cess. It's another aspect of the modular future for CDMOs." Patheon expects to install the pro- cess equipment mid-year, after which it will be connected to the control system. "We'll make sure that our process has the capability to run sta- ble so that we can bring our client's valuable material to the line with the confidence that we can produce the best product on it and not have a waste issue or deviations." In the meantime, Patheon is talking with clients about which products are a good fit for the line. Large production volumes favor continuous manufacturing, but that's not likely to be the primary consider- ation, Jayjock said. "I think the most value will come from developing a product on a continuous line because it will save API early and you'll get more knowledge about the line, and thus more confidence in your pro- cess." It will also eliminate scaleup. "Those are huge advantages for a new product." Patheon is the first CDMO to under- take continuous pharmaceutical manu- facturing. "There's only a handful of companies that have the technical capa- bility and the depth of staff to handle it at this point. At Patheon, we're working to be an industry leader. Our goal is to be the go-to place for continuous manu- facturing in the oral solid dosage realm." - M.K sales@ackleymachine.com www.ackleymachine.com PRINT. INSPECT. X2. Now you can print with pixel precision and inspect both the printed logo and second surface side in one pass – all with our new Cantilever Ramp Printer with Vision Inspection. You've invested heavily in your brand so make sure it's recognized. Turn to Ackley to ensure a perfect brand presentation each and every time. Why settle for anything less? Call Ackley at 856-234-3626 today! Featuring: • Fail safe synchronized tablet vacuum ejection drum system for single tablet rejection • Quick-release carrier bars for easy change-over to other products • Safety interlocked machine guarding • Adjustable vision system parameters from touch-screen monitor sales@ackleymachine com p monitor WITH PIXEL PRECISION. For more information about contin- uous manufacturing of solid dosage forms, see the May 2015 article, "Arden House conference: Continuous manufacturing gains momentum." It summarizes a 3-day AAPS event that featured Jayjock and other speakers from the pharmaceutical industry, the FDA, and academia. Another article, "Evaluation of a continuous-cycled film coater in applying a high-solids coating," appeared in the October 2015 issue. It summarizes a study conducted by Colorcon and Driam. The coated tablets were assessed for weight gain consistency, color uniformity, surface roughness, and gloss. Both articles are available at no cost when you log in to www.tabletscap sules.com and at these links: bit.ly/Arden2015 bit.ly/TC1015ContinCoat