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Tablets & Capsules April 2018 23 A Multiple factors, including costs, medical condition, and complexity of regimen, play a role in adherence rates. Lack of patient adherence often leads to worsening health and poor outcomes and increases costs across the healthcare system. Taste masking can contribute to improved drug acceptability and medication adherence, particularly in pediatric, geriatric, and other special patient populations. This article describes current taste- masking methods and highlights areas where effective taste-masking formulation techniques can play a role. Basic considerations for taste masking When the taste and palatability of a drug product's active pharmaceutical ingredient (API) is likely to be The development and optimization of taste-masking formulations, especially for pediatric drug products, continues to be an important aspect of solid oral dosage formulation. This article examines several techniques to overcome the bitter or unpleasant taste of some active pharmaceutical ingredients. lthough many effective pharmaceutical treatments exist, a recent Institute of Medicine report identified a gap between actual treatment success rates and those believed to be achievable. This gap has been attributed partly to a lack of patient adherence to recommended medication regimens [1]. Bitter to Better: Formulation strategies for effective taste masking Charles Vesey Colorcon taste masking