Inhalation

INH0616

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anism of inhalation profile improvement of DPI formu- lations by mechanofusion with magnesium stearate. Chemical and Pharmaceutical Bulletin 56(5):617-625. 27. Zhou QT, Armstrong B, Larson I, Stewart PJ, Mor- ton DAV, 2010. Understanding the influence of pow- der flowability, fluidization and de-agglomeration char- acteristics on the aerosolization of pharmaceutical model powders. European Journal of Pharmaceutical Sciences 40(5):412-421. 28. Zhou QT, Qu L, Larson I, Stewart PJ, Morton DA, 2011. Effect of mechanical dry particle coating on the improvement of powder flowability for lactose monohy- drate: A model cohesive pharmaceutical powder. Pow- der Technology 207(1):414-421. 29. Zhou QT, Qu L, Larson I, Stewart PJ, Morton DA, 2010. Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach. International Journal of Pharmaceu- tics 394(1):50-59. 30. Morton D, Qi ZT, Musa R, 2012. Antibiotic microparticles for inhalation. US 20110139152 A1, International Patent Application WO/2011/073002. 31. Das SC, Zhou Q, Morton DA, Larson I, Stewart PJ, 2011. Use of surface energy distributions by inverse gas chromatography to understand mechanofusion process- ing and functionality of lactose coated with magnesium stearate. European Journal of Pharmaceutical Sciences 43(4):325-333. 32. Zhou QT, Denman JA, Gengenbach T, Das S, Qu L, Zhang H, Larson I, Stewart PJ, Morton DA, 2011. Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharma- ceutical lubricant to improve flow via a mechanical dry coating approach. Journal of Pharmaceutical Sciences 100(8):3421-3430. 33. Fadley CS, Baird RJ, Siekhaus W, Novakov T, Bergström, SÄL, 1974. Surface analysis and angular dis- tributions in x-ray photoelectron spectroscopy. Journal of Electron Spectroscopy and Related Phenomena 4(2):93-137. 34. Powell CJ, Larson PE, 1978. Quantitative surface analysis by X-ray photoelectron spectroscopy. Applica- tions of Surface Science 1(2):186-201. 35. Carter WJ, Schweitzer GK, Carlson TA, 1974. Experimental evaluation of a simple model for quantita- tive analysis in X-ray photoelectron spectroscopy. Jour- nal of Electron Spectroscopy and Related Phenomena 5(1):827-835. Li Qu, MSc is a PhD candidate at Monash Institute of Phar- maceutical Sciences, Monash University, Melbourne, VIC 3052, Australia. David A.V. Morton is an Associate Professor at Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC 3052, Australia. Qi (Tony) Zhou is an Assistant Professor at the Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue Uni- versity, 575 Stadium Mall Drive, West Lafayette, IN, 47907-2091, US, tonyzhou@purdue.edu. 22 JUNE 2016 Inhalation R a l a h n I o i t a n o e c r u o s e R s ' r e y u B & e c n e r e f e R n a o i t a l a h n I 6 1 0 2 n R e R ef ŝ Ŷ Ă Ő ƌ Ž Ă ů Ă Ś Ŷ / ǀ Ɛ ŝ Ś d & erence f R B e R B esource! B uyer's Ś Ś Ɖ Ɖ ͕ Ɛ ƌ Ğ ŝ ů Ɖ Ɖ Ƶ ŵ Ɛ ͕ Ɛ Ŷ Ž Ɵ Ă nj ŝ Ğ Ž Đ Ă Ɛ Ğ Ě Ž ŝ ǀ Ž ƌ Ɖ Ŷ Ž Ɵ Ă Ž ƌ Ĩ Ğ Đ ƌ Ƶ Ž Ɛ Ğ ƌ Ğ ů ď Ă Ƶ ů Ă ǀ Ś Ě Ŷ Ă Ɛ ƚ Đ Ƶ Ě Ž ƌ Ɖ Ĩ Ž Ŷ Ž Ɵ Ă ů ŝ Ɖ ŵ ŵ ͕ ƚ ŝ Ě Ă Ž ů Ŷ ǁ Ž ǁ Ğ ǁ ǁ ů Ă Ś Ŷ ŝ Ž ů Ğ ǀ Ğ Ě Đ ŝ ǀ ƌ Ğ Ɛ ƚ ŵ ŝ Ő ŝ Ě Ͳ Ğ ͘ ǁ Ŭ Ž Ž ď ͞ ƌ Ž LJ Ɖ Ž Đ Ă ƚ Ŷ ŝ ƌ Ɖ Ğ ͘ Ɛ ů Ă Đ Ɵ Ƶ Ğ Đ Ɖ Ă ŵ ƌ Ă Ś Ɖ Ě Ă Ğ Ě Ĩ Ƶ Ŷ Ă ŵ ƌ Ŷ Ă ƚ Ŷ Ğ ŵ Ɖ Ž Ɖ Ğ Ś ƚ ƚ ƌ Ž Ɖ Ɖ Ƶ Ɛ ƚ Ă Ś ƚ Ɛ Ğ Đ ϵ Ś Ϯ Ϯ Ϯ ϲ ͬ ŝ ͬ ŵ Ž Đ ͘ Ɛ Ŷ Ž Ɵ ŝ Ě Ğ ů Ă ƚ Ő Ƶ Ž ƌ Ś ƚ Ğ Ɛ Ƶ ƌ Ž Ĩ ƚ ŝ ͟ Ŭ ƌ Ă ŵ Ĩ Ž Ő Ŷ ŝ ƌ Ƶ ƚ Đ ͕ Ś Đ ƌ Ă Ğ Ɛ Ğ ƌ ͘ ϲ Ś ϭ ϭ Ϭ Ͳ Ő ď Ͳ Ś Ŷ ŝ Ͳ ϭ ͘ ƌ͘ ƌ͘ Ă Ğ LJ Ğ Ś ƚ ƚ Ƶ Ž Ś

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