Issue link: https://www.e-digitaleditions.com/i/1233462
10 April 2020 Tablets & Capsules preventing cortisol synthesis. The drug is manufactured by Novartis, Basel, Switzerland. Brieftly noted… The FDA approved Nerlynx (neratinib) in combination with capecitabine for adult patients with advanced or metastatic HER2-posi- tive breast cancer who have received two or more prior anti-HER2-based regimens. It is manufactured by Puma Biotechnology, Los Angeles, CA. The agency also approved Nexle- tol (bempedoic acid) as a non-statin treatment to lower LDL cholesterol. It is manufactured by Esperion, Ann Arbor, MI. The FDA approved the first generic for Daraprim (pyrimeth- amine), which treats toxoplasmosis when used with a sulfonamide med- ication. The approved generic is manufactured by Cerovene, Valley Cottage, NY, and Daraprim is man- ufactured by Vyera Pharmaceuticals, New York, NY. method for clinical trials that is faster and cheaper than conventional meth- ods. It would also allow for flexible and sustainable local tablet production that would meet patients' needs. FDA approves first ILD and Cushing's treatments SILVER SPRING, MD— The FDA approved Ofev (nintedanib) to treat patients with chronic fibrosing (scar- ring) interstitial lung diseases (ILD) with a progressive phenotype. It is the first FDA-approved treatment for this group of fibrosing lung diseases. Ofev is manufactured by Boehringer Ingel- heim Pharmaceuticals, Ridgefield, CT. The agency also approved Istur- isa (osilodrostat) as a treatment for adults with Cushing's disease who either cannot undergo pituitary gland surgery or have undergone the surgery but still have the disease. The product is the first FDA-ap- proved drug to directly address cor- tisol overproduction associated with Cushing's by blocking the enzyme known as 11-beta-hydroxylase and gram selected various participants to explore and evaluate methods to enhance the safety and security of the drug supply chain. The MediLedger Pilot Project was comprised of 25 companies that evaluated blockchain technologies like the MediLedger Network to track and trace prescrip- tion drugs across the US pharmaceu- tical supply chain. The final report proposed business rules and standards on data sharing and using a block- chain-based network to enforce those standards. To read the full report, please visit www.mediledger.com/ fda-pilot-project. Merck and AMCM partner on 3D tablet printing DARMSTADT, Germany—Merck and Additive Manufacturing Custom- ized Machines (AMCM), Starnberg, Germany, have agreed to partner on a 3D-printed tablet project. AMCM is a sister company of 3D printing sup- plier EOS. The partnership's goal is to create a GMP-conforming tablet for- mulation development and production EXPERIENCE THE DIFFERENCE THE ELIZABETH DIFFERENCE. Compression Tooling | Tablet Presses | Turrets | Replacement Parts| Field Services & Training Blister Packaging Tooling & Feeders | Tablet Press & Turret Repairs We understand that your products are trusted by consumers each and every day. Consistent quality of your solid dose products is expected and non-negotiable. Your products depend upon the integrity of your equipment and tooling. For over 65 years, Elizabeth Companies have put a personal guarantee on customer satisfaction and takes pride in delivering innovative solutions. We promise our customers an unequaled level of customer service, trust, product performance, and prompt & courteous communication. ELIZ.COM | 412-751-3000 @ELIZCOMPANIES