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16 April 2020 Tablets & Capsules pore-former on drug release from ethylcellulose coated multiparticulates," 37th CRS Annual Meeting, 2010. 4. J. Teckoe and A. R. Rajabi-Siahboomi, "Investiga- tion of Taste Masking Performance of an Aqueous Ethyl- cellulose Dispersion (Surelease Ethylcellulose Dispersion Type B NF) on Acetaminophen Granules," AAPS Annual Meeting, 2013. 5. "Use of Surelease and Opadry in the Develop- ment of a Paediatric Form of Raltegravir for the European Union," Colorcon website: www.colorcon.com. 6. "Film Coating for Pediatric Oral Solid Dosage Forms," White Paper, Colorcon website: www.colorcon. com. 7. Herbert A. Lieberman, L. Lachman, and J. B. Schwartz, Pharmaceutical Dosage Forms: Tablets, Vol.1, 2nd Edition, CRC Press, pages 387-391. 8. Bob Oas, "Making bitter-tasting APIs palatable using the right combination of excipients," Tablets & Cap- sules, July 2006, pages 12-18. Federica Giatti is process development technologist, R&D labo- ratory, Massimo Malavolti is product manager, coating equipment, Fabriano Ferrini is product manager, tableting and encapsulation, and Caterina Funaro is process laboratory manager at IMA Active, a manufacturer of solid dose process- ing equipment (+39 051 6514111, www.ima.it). obtain a range of drug-release profiles. All materials used in this study have precedence of use in pediatric applications. The tableting process was challenging compared to standard tablet compression, but it was stable and not problematic. The slotted-screen drum design proved to be a suitable technology for coating minitablets for taste-masking purposes. The coater has a much smaller footprint for the same batch size than a fluid-bed coating process, and the spray guns are accessible during the pro- cess. The drum did not cause abrasion or damage to the minitablets and allowed for a high inlet-air volume and a high spray rate, resulting in economical process times similar to those of conventional perforated-drum coat- ers. Additionally, the process is easily controllable, which simplifies scale-up. T&C References 1. C. Funaro, G. Mondelli, N. Passerini, and B. Albertini, "Minitablets coated in a solid-wall pan for the- ophylline sustained-release capsules," Pharmaceutical Tech- nology, 2010, No. 6, pages 38-42. 2. L. Baginski, F. Bang, T. Cech, F. Cembali, C. Funaro, and G. Mondelli, "Evaluating an alternative to fluid bed technology for drug layering and for apply- ing functional coats onto pellets," 39th CRS Annual Meeting, 2012. 3. D. V. Diad, V. Ambudkar, R. Steffenino, T. Far- rell, and A. R. Rajabi-Siahboomi, "The influence of sotax.com/xtend Solutions for Pharmaceutical Testing Ready for tomorrow. Today. Respond flexibly to changing workloads and simplify method transfer with the Xtend ™ Dissolution Line. Standardized modules such as dissolution bath, pump, and sample manager can be flexibly combined or extended anytime – from manual to semi- and fully automated systems. Ready for tomorrow. Today. Respond flexibly to changing workloads and simplify method transfer Modular. Scalable. Future-proof. Xtend ™