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Inhalation August 2020 21 Measurement of airborne aerosols The Aerosol Optical Tweezer (AOT) instrument was developed in collaboration with Bristol Univer- sity's Aerosol Research Centre. Unlike other aero- sol instruments, the AOT-100 allows users to hold airborne droplets for extended periods in an optical trap, which enables many parameters to be measured continuously, over times varying from milliseconds to hours. e AOT-100 offers a genuine step-change for achievement in the measurement of airborne aerosols. ese measurements include droplet radius, refractive index, viscosity and surface tension. Biral UK: +44 1275 847787 www.biral.com Automated shake and fire system The Vertus II automated sha ke and f ire system enhances metered dose inhaler (MDI) testing data accuracy by eliminating firing errors and reducing variability. Compatible with most inhalers and a wide range of dose collection devices, including the Dos- age Unit Sampling Apparatus (DUSA), Andersen Cascade Impactor (ACI), Next Generation Impactor (NGI) and Glass Twin Impinger (GTI), the Vertus II offers complete control over the test technique, including shaking profile, angle of fire, the time delay between shaking and firing, and inhaler resting posi- tion. Achieve all this and automate shot weight collec- tion with the Vertus Plus. Copley Scientific UK: +44 1159 616229 www.copleyscientific.com Aerosol characterization for in vivo dosing PreciseInhale ® can perform a complete PK study with < 100 mg of dry powder (active pharmaceutical ingre- dient (API)). It generates particle size distribution (PSD) data for the generated aerosol using a Marple Cascade Impactor, connected to PreciseInhale with a specially adapted dilution tunnel. e PSD data is used to ensure precision dosing, the signature benefit of PreciseInhale. With multiple path particle dosim- etry (MPPD) modeling based on PSD, the estimated lung- deposited dosage is used to set the inhaled target dose, measured during exposure, generating extraor- dinarily low standard deviations. Inhalation Sciences Sweden: +46 705 625 195 www.inhalation.se