Inhalation

INH0820

Issue link: https://www.e-digitaleditions.com/i/1276475

Contents of this Issue

Navigation

Page 28 of 35

Inhalation AUGUST 2020 27 13. Verma S, Kumar S, Gokhale R, et al. Physical sta- bility of nanosuspensions: Investigation of the role of stabilizers on Ostwald ripening. International Journal of Pharmaceutics. 2011. 406: 145-52. 14. Anderson SD, Brannan JD. Bronchial provocation testing and collection of sputum with inhaled man- nitol. Clinical and Experimental Allergy. 2010. 40: 193-196. 15. Hassan MS, Lau RW. E ect of particle shape on dry particle inhalation: Study of owability, aerosoliza- tion, and deposition properties. AAPS PharmSciTech. 2009. 10(4): 1252-1262. Cameron Kadleck, BSE, is a Respiratory Scientist, Prod- uct Development, Joseph Churchman, BSc, is a Respira- tory Scientist, Product Development and Herbert Chiou, PhD, MRACI CChem, is a Principal Investigator at Lonza, inhalation@lonza.com, https://pharma.lonza. com. Corresponding author: Herbert Chiou, PhD, MRACI CChem, Principal Investigator, Lonza, 64550 Research Road, Bend, OR, 97701, US, Tel.: +1 541 706-8237, Herbert.Chiou@lonza.com. 6. Wang YB, Watts AB, Peters JI, et al. In vitro and in vivo performance of dry powder inhalation formu- lations: Comparison of particles prepared by thin lm freezing and micronization. AAPS PharmSciTech. 2014. 15(4): 981-993. 7. Tsai W-C, Wang Y. Progress of supercritical uid technology in polymerization and its applications in biomedical engineering. Progress in Polymer Science. 2019. 98: 101-161. 8. Chiou H, Chan HK, Heng D, et al. A novel produc- tion method for inhalable cyclosporine A powders by con ned liquid impinging jet precipitation. Journal of Aerosol Science. 2008. 39(6): 500-509. 9. Hu T, Chiou H, Chan HK, et al. Preparation of inhalable salbutamol sulphate using reactive high grav- ity controlled precipitation. Journal of Pharmaceutical Sciences. 2008. 97(2): 944-949. 10. Loh ZH, Samanta AK, Heng PWS. Overview of milling techniques for improving the solubility of poorly water-soluble drugs. Asian Journal of Pharma- ceutical Sciences. 2015. 10(4): 255-274. 11. Huang D, Rao N, Tan T, et al. Spray-dried solid- in-oil-in-water dispersions for inhalation of active pharmaceutical ingredients. US Patent Application US20170007547A1. 12. Simkova K, Stalder J, Stebler F, et al. Use of addi- tives in particle engineering of spray-dried nanosus- pensions. Drug Delivery to the Lungs 26. 2015. LEARN MORE: www.proveris.com contactus@proveris.com +1 508 460-8822 Scientific expertise and testing strategies for innovator and generic OINDPs • Human Usage Studies • Device Selection • Formulation Screening Alternative BE Studies • Regional Drug Deposition • Plume Velocity • Evaporation Fraction • In Vitro Testing • Drug Product Characterization Studies • Priming/Repriming • Temperature Cycling • Device Robustness • Stability Studies • Batch Release Testing • Long-term Stability Testing • Root Cause Analysis • OOS/OOT Investigation FROM DEVELOPMENT TO COMMERCIALIZATION YOUR PARTNER… NOW FEATURING cGMP COMPLIANT LABORATORY

Articles in this issue

Links on this page

view archives of Inhalation - INH0820