Inhalation

INH0622

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This section provides information that may be useful in research and development or manufacturing. Content is provided by the companies listed. No endorsement or preference is intended. 20 June 2022 Inhalation ISSUE FOCUS Nasal Delivery, Nebulizers and Soft Mist Inhalers This section of Inhalation provides information that may be useful in research and development or manufacturing. Content is provided by the companies listed. No product endorsement or preference is intended. Multi-dose soft mist inhaler Merxin's MRX004 is a multi-dose soft mist inhaler for deep lung deposition and easy use, designed for aqueous and ethanol formulations. It is ideal for new molecules and life cycle management, particularly for those products that would benefit from a reduced dose. e MRX004 can be used with molecules that would benefit from lung delivery, for local action or systemic delivery, or re-purposing existing molecules away from nebulizers, dry powder inhalers (DPIs) or pressurized metered dose inhalers (pMDs) into a much more efficient and greener device. Merxin UK: +44 1553 406070 info@merxin.com www.merxin.com Alberta Idealised Nasal Inlet (AINI) e Alberta Idealised Nasal Inlet (AINI) is an import- ant step forward in terms of achieving more clinically representative nasal product testing and is particularly valuable for the demonstration of bioequivalence. Made up of four individual regions—the vestibule, turbinate, olfactory and nasopharynx—the AINI mimics deposition behavior in each while simultane- ously generating a sample that accurately reflects the respirable dose. Find out more: bit.ly/Copley-AINI Copley Scientific UK: +44 1159 616229 sales@copleyscientific.co.uk www.copleyscientific.com Integrated, end-to-end services Hovione offers end-to-end service for particle-based and inhalation products. With more than 20 years of expertise in the development and marketing of inno- vative inhalation devices, we offer dry powder inhalers that are simple, patented and cost-effective. Crystalli- zation, jet milling and wet milling spray-drying pro- cesses are developed using a quality by design (QbD) approach to deliver the physical, chemical and micro- biological critical quality attributes of the active phar- maceutical ingredient. Hovione also offers a complete portfolio of platforms suitable for both innovator and generic development. Hovione Portugal: +351 21 982 9000 www.hovione.com

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