Inhalation

INH0622

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Technical articles discuss use of computational fluid dynamics (CFD) modeling for design and performance analysis of nasal sprays and present the first part of a two-part series on formulation development of adhesive mixtures for inhalation. The Cross-industry organizations column provides an update from ISAM. The Back page article describes research on health effects of long-term exposure to levels of air pollution below government-recommended standards. 2 June 2022 Inhalation Inhalation (ISSN 1937-0717 print; ISSN 1940-414X online) is published seven times per year in January, February, April, June, August, October and December by Whipsnade and Loophole, LLC, P.O. Box 27092, Minneapolis, MN 55427 US. w w w . i n h a l a t i o n m a g . c o m June 2022 Volume 16 Number 3 New in vitro test methods for nasal drug products, such as the Alberta Idealised Nasal Inlet (AINI), can deliver enhanced IVBE studies for generics and support development of novel intranasal prod- ucts targeting specific nasal regions. Courtesy of Intertek Melbourn, Saxon Way, Melbourn, Hertfordshire, SG8 6DN, United Kingdom, Tel.: +44 1763 261648, bd.melbourn@intertek.com, www.intertek.com nasal delivery, nebulizers and soft mist inhalers 10 Use of computational fluid dynamics (CFD) modeling for design and performance analysis of nasal sprays Arun V. Kolanjiyil and Worth Longest 20 Issue focus: Nasal delivery, nebulizers and soft mist inhalers additional features 6 Cross-industry organizations: ISAM: 2021 highlights and a preview of 2022 activities Barbara Rothen-Rutishauser 24 Formulation development of adhesive mixtures for inhalation—A multi-factorial optimization challenge: Part 1 Kyrre Thalberg 32 Special section: Filling and packaging 37 Back page: Study provides first comprehensive global estimates of PM 2.5 sources and cause-specific disease burden departments 8 Industry news 34 Calendar 35 Products and services

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